5-HT7激动剂1

• 常用名: 5-HT7激动剂1
• 英文名: 5-HT7 agonist 1
• CAS号: 334974-31-1
• 分子量: 325.83500
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₀ClN₃
• 熔点: N/A
• 闪点: N/A

5-HT7激动剂1用途

5-HT7 agonist 1 是一种选择性的 5-HT7 受体激动剂,IC50 值为 222.93 nM,可用于研究与 5-HT7 受体相关的疾病,例如中枢神经系统疾病。

5-HT7激动剂1名称

• 中文名: 5-HT7激动剂1
• 英文名: [33] 4-(4-(2-chlorobenzyl)piperazin-1-yl)-1H-indole

5-HT7激动剂1生物活性

• 描述: 5-HT7 agonist 1 是一种选择性的 5-HT7 受体激动剂,IC50 值为 222.93 nM,可用于研究与 5-HT7 受体相关的疾病,例如中枢神经系统疾病。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体
  信号通路 >> 神经信号通路 >> 5-HT受体
  研究领域 >> 神经疾病
• 靶点实验:

  IC50: 222.93 nM (5-HT7 receptor)[1]

• 体外研究: 5-HT7激动剂1(化合物33)是一种选择性5-HT7受体激动剂,IC50为222.93 nM,可用于5-HT7受体相关疾病,如CNS疾病[1]。
• 参考文献:

  [1]. Pascual-ramon, et al. 5HT7 RECEPTOR LIGANDS AND COMPOSITIONS COMPRISING THE SAME. 20110183991 A1.

5-HT7激动剂1物理化学性质

• 分子式: C₁₉H₂₀ClN₃
• 分子量: 325.83500
• 精确质量: 325.13500
• PSA: 22.27000
• LogP: 4.14640
• InChIKey: IKHUKLQDWXAECD-UHFFFAOYSA-N
• SMILES: Clc1ccccc1CN1CCN(c2cccc3[nH]ccc23)CC1

5-HT7激动剂1靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2 来源：NCGC 靶标：eyes absent homolog 2 isoform a [Homo sapiens] External Id：EYA2477

实验名称：Luminescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of ADP-glo R... 来源：Broad Institute 靶标：N/A External Id：2046-03_INHIBITORS_DOSE-TITRATION_MLPCN-CHERRYPICK

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Bas... 来源：Broad Institute 靶标：N/A External Id：2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2

实验名称：Primary cell-based high-throughput screening for identification of compounds that all... 来源：Johns Hopkins Ion Channel Center 靶标：MAS-related GPR member X1 [Homo sapiens] External Id：JHICC_MrgX1_AlloAgonist_Primary

实验名称：Primary cell-based high-throughput screening for identification of compounds that ant... 来源：Johns Hopkins Ion Channel Center 靶标：MAS-related GPR member X1 [Homo sapiens] External Id：JHICC_MrgX1_Antagonist_Primary

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