A-315675

• 常用名: A-315675
• 英文名: A-315675
• CAS号: 335679-69-1
• 分子量: 326.43100
• 密度: 1.101g/cm3
• 沸点: 520.9ºC at 760 mmHg
• 分子式: C₁₇H₃₀N₂O₄
• 熔点: N/A
• 闪点: 268.8ºC

A-315675用途

A-315675 是高效的 A 株和 B株流感病毒神经氨酸酶的抑制剂。

A-315675名称

• 英文名: (2R,4S,5R)-5-[(1R,2S)-1-acetamido-2-methoxy-2-methylpentyl]-4-[(Z)-prop-1-enyl]pyrrolidine-2-carboxylic acid

A-315675生物活性

• 描述: A-315675 是高效的 A 株和 B株流感病毒神经氨酸酶的抑制剂。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Warren M Kati, et al. In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication. Antimicrob Agents Chemother. 2002 Apr;46(4):1014-21.

A-315675物理化学性质

• 密度: 1.101g/cm3
• 沸点: 520.9ºC at 760 mmHg
• 分子式: C₁₇H₃₀N₂O₄
• 分子量: 326.43100
• 闪点: 268.8ºC
• 精确质量: 326.22100
• PSA: 91.15000
• LogP: 2.87280
• InChIKey: UUVKABIGWGMYCE-FLMGFEAJSA-N
• SMILES: CC=CC1CC(C(=O)O)NC1C(NC(C)=O)C(C)(CCC)OC
• 折射率: 1.523

A-315675靶点实验

查看更多实验

实验名称：Ratio of IC50 for influenza A (A/Singapore/91/2009 (H1N1)) virus harboring neuraminid... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664839

实验名称：Ratio of IC50 for influenza A (A/North Carolina/01/2009 (H1N1)) virus harboring neura... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664840

实验名称：Ratio of IC50 for influenza A (A/Montana/02/2009 (H1N1)) virus harboring neuraminidas... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664841

实验名称：Ratio of IC50 for influenza A (A/Osaka/180/2009 (H1N1)) virus harboring neuraminidase... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664842

实验名称：Ratio of IC50 for influenza A (A/Washington/29/2009 (H1N1)) virus harboring neuramini... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664843

实验名称：Ratio of IC50 for influenza A (A/Hong Kong/2369/2009 (H1N1)) virus harboring neuramin... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664844

实验名称：Ratio of IC50 for influenza A (A/Singapore/57/2009 (H1N1)) virus harboring neuraminid... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664845

实验名称：Ratio of IC50 for influenza A (A/North Carolina/02/2009 (H1N1)) virus harboring neura... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664846

实验名称：Ratio of IC50 for influenza A (A/North Carolina/02/2009 (H1N1)) virus harboring neura... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664837

实验名称：Ratio of IC50 for influenza A (A/New York/18/2009 (H1N1)) virus harboring neuraminida... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1664838

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A-315675英文别名

• D-Proline,5-[(1R,2S)-1-(acetylamino)-2-methoxy-2-methylpentyl]-4-(1Z)-1-propenyl-,(4S,5R)
• (5R)-((1R)-acetylamino-(2S)-methoxy-(2S)-methylpentyl)-(4S)-Z-propenylpyrrolidine-(2R)-carboxylic acid
• 5-[(1R,2S)-1-(acetylamino)-2-methoxy-2-methylpentyl]-4-[(1Z)-1-propenyl]-(4S,5R)-D-proline
• (-)-(2R,4S,5R)-5-[(1R,2S)-1-(acetylamino)-2-methoxy-2-methylpentyl]-4-[(1Z)-prop-1-enyl]pyrrolidine-2-carboxylic acid
• 5-[(2S,1R)-1-(Acetylamino)-2-methoxy-2-methylpentyl](4S,2R)-4-(prop-1-enyl)pyrrolidine-2-carboxylic acid
• (+-)-(2R,3S,5R,1'R,2'S)-2-(1-Acetamido-2-methyl-2-methoxy)pentyl-3-(cis-propen-1-yl)-pyrrolidine-5-carboxylic Acid