2-十八烯酸单甘油酯

更新时间:2024-01-04 22:25:00

2-十八烯酸单甘油酯结构式
2-十八烯酸单甘油酯结构式
品牌特惠专场
常用名 2-十八烯酸单甘油酯 英文名 2-Oleoylglycerol
CAS号 3443-84-3 分子量 356.54000
密度 0.969 g/cm3 沸点 485.4ºC at 760mmHg
分子式 C21H40O4 熔点 N/A
MSDS 中文版 美版 闪点 113ºC

 2-十八烯酸单甘油酯用途


2-Oleoylglycerol 是饮食中天然存在的脂质。2-Oleoylglycerol 是一种 GPR119 激动剂,在瞬时转染的 COS-7 细胞中激活 hGPR119 的 EC50 值为 2.5 μM。2-Oleoylglycerol 在体内刺激胰高血糖素样肽 1 (GLP-1) 分泌。

 2-十八烯酸单甘油酯名称

中文名 2-十八烯酸单甘油酯
英文名 2-oleoylglycerol
中文别名 2-甘油单油酸酯
英文别名 更多

 2-十八烯酸单甘油酯生物活性

描述 2-Oleoylglycerol 是饮食中天然存在的脂质。2-Oleoylglycerol 是一种 GPR119 激动剂,在瞬时转染的 COS-7 细胞中激活 hGPR119 的 EC50 值为 2.5 μM。2-Oleoylglycerol 在体内刺激胰高血糖素样肽 1 (GLP-1) 分泌。
相关类别
靶点

IC50: 2.5 μM (hGPR119) (in COS-7 cells)[1]

参考文献

[1]. Hansen KB, et, al. 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. J Clin Endocrinol Metab. 2011 Sep;96(9):E1409-17.

[2]. Ghafouri N, et, al. Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. Br J Pharmacol. 2004 Nov;143(6):774-84.

 2-十八烯酸单甘油酯物理化学性质

密度 0.969 g/cm3
沸点 485.4ºC at 760mmHg
分子式 C21H40O4
分子量 356.54000
闪点 113ºC
精确质量 356.29300
PSA 66.76000
LogP 4.92030
外观性状 液体
折射率 1.478
储存条件 -20°C, 密封, 避光

 2-十八烯酸单甘油酯安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
WGK德国 3

 2-十八烯酸单甘油酯合成线路

 2-十八烯酸单甘油酯文献15

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 2-十八烯酸单甘油酯英文别名

glycerine monooleate
2-o-Kresyloxy-glutarsaeure-diethylester
2-MONOOLEIN
1,3-dihydroxypropan-2-yl oleate
2-monooleoylglycerol
2-Oleoylglycerol
glycerin oleate
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