2-Oleoylglycerol
2-Oleoylglycerol structure
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Common Name | 2-Oleoylglycerol | ||
|---|---|---|---|---|
| CAS Number | 3443-84-3 | Molecular Weight | 356.54000 | |
| Density | 0.969 g/cm3 | Boiling Point | 485.4ºC at 760mmHg | |
| Molecular Formula | C21H40O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 113ºC | |
Use of 2-Oleoylglycerol2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-oleoylglycerol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.5 μM (hGPR119) (in COS-7 cells)[1] |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 0.969 g/cm3 |
|---|---|
| Boiling Point | 485.4ºC at 760mmHg |
| Molecular Formula | C21H40O4 |
| Molecular Weight | 356.54000 |
| Flash Point | 113ºC |
| Exact Mass | 356.29300 |
| PSA | 66.76000 |
| LogP | 4.92030 |
| Index of Refraction | 1.478 |
| InChIKey | UPWGQKDVAURUGE-KTKRTIGZSA-N |
| SMILES | CCCCCCCCC=CCCCCCCCC(=O)OC(CO)CO |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 4 | |
CAS#:851768-15-5
CAS#:112-80-1
CAS#:56-81-5
CAS#:122-32-7
CAS#:112-77-6
CAS#:1708-40-3
CAS#:33001-45-5
CAS#:112-62-9
CAS#:5431-33-4
CAS#:2190-27-4
CAS#:111-03-5
CAS#:3343-30-4
CAS#:3123-73-7This table lists relevant public references with title, journal and publication metadata for this compound.
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Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol.
J. Physiol. 593(8) , 2097-109, (2015) Sensing of dietary triacylglycerol in the proximal small intestine results in physiological, hormonal and behavioural responses. However, the exact physiological pathways linking intestinal fat sensin... |
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TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.
Am. J. Physiol. Lung Cell. Mol. Physiol. 307(2) , L158-72, (2014) The treatment of acute lung injury caused by exposure to reactive chemicals remains challenging because of the lack of mechanism-based therapeutic approaches. Recent studies have shown that transient ... |
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Identification of 2-[2-(4-tert-butylphenyl)ethyl]-N-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide (29) as an orally available MGAT2 inhibitor.
Bioorg. Med. Chem. 23 , 5922-31, (2015) MGAT2 (monoacylglycerol acyltransferase 2) is expected to be an attractive target for the drug treatment of obesity, diabetes, and other disease. We describe our exploration and structure-activity rel... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| glycerine monooleate |
| 2-o-Kresyloxy-glutarsaeure-diethylester |
| 2-MONOOLEIN |
| 1,3-dihydroxypropan-2-yl oleate |
| 2-monooleoylglycerol |
| 2-Oleoylglycerol |
| glycerin oleate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of 2-oleoylglycerol? |
| A: Polar surface area (PSA) of 2-oleoylglycerol is 66.76000. |
| Q: What are the downstream products of 2-oleoylglycerol? |
| A: Related downstream products(CAS) of 2-oleoylglycerol: 2190-27-4;111-03-5;3343-30-4;3123-73-7. |
| Q: What are the upstream materials of 2-oleoylglycerol? |
| A: Related upstream materials(CAS) of 2-oleoylglycerol: 851768-15-5;112-80-1;56-81-5;122-32-7;112-77-6;1708-40-3;33001-45-5;112-62-9;5431-33-4. |
| Q: What English synonyms does 2-oleoylglycerol have? |
| A: English synonyms of 2-oleoylglycerol: glycerine monooleate, 2-o-Kresyloxy-glutarsaeure-diethylester, 2-MONOOLEIN, 1,3-dihydroxypropan-2-yl oleate, 2-monooleoylglycerol, 2-Oleoylglycerol, glycerin oleate. |
| Q: What is the LogP of 2-oleoylglycerol? |
| A: LogP of 2-oleoylglycerol is 4.92030. |
| Q: What is the SMILES notation of 2-oleoylglycerol? |
| A: SMILES notation of 2-oleoylglycerol is CCCCCCCCC=CCCCCCCCC(=O)OC(CO)CO. |
| Q: What is the InChIKey of 2-oleoylglycerol? |
| A: InChIKey of 2-oleoylglycerol is UPWGQKDVAURUGE-KTKRTIGZSA-N. |
| Q: What are the uses of 2-oleoylglycerol? |
| A: Main uses of 2-oleoylglycerol: 2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo[1][2]. |
| Q: What is the molecular formula of 2-oleoylglycerol? |
| A: Molecular formula of 2-oleoylglycerol is C21H40O4. |
| Q: What is the molecular weight of 2-oleoylglycerol? |
| A: Molecular weight of 2-oleoylglycerol is 356.54000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |