托屈嗪 盐酸盐

• 常用名: 托屈嗪 盐酸盐
• 英文名: Todralazine hydrochloride
• CAS号: 3778-76-5
• 分子量: 268.70000
• 密度: 1.328g/cm3
• 沸点: N/A
• 分子式: C₁₁H₁₃ClN₄O₂
• 熔点: N/A
• 闪点: N/A

托屈嗪 盐酸盐用途

Todralazine hydrochloride (Ecarazine hydrochloride) 是一种抗高血压剂,为 β2 肾上腺素能受体 (β2AR) 阻滞剂,具有抗氧化、清除自由基的活性。

托屈嗪 盐酸盐名称

• 中文名: 托屈嗪 盐酸盐
• 英文名: ethyl N-(phthalazin-1-ylamino)carbamate,hydrochloride
• 中文别名: 盐酸托屈嗪

托屈嗪 盐酸盐生物活性

• 描述: Todralazine hydrochloride (Ecarazine hydrochloride) 是一种抗高血压剂,为 β2 肾上腺素能受体 (β2AR) 阻滞剂,具有抗氧化、清除自由基的活性。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
• 靶点实验:

  β2AR[1]

• 参考文献:

  [1]. Dimri M, et al. Todralazine protects zebrafish from lethal effects of ionizing radiation: role of hematopoietic cell expansion. Zebrafish. 2015 Feb;12(1):33-47.

托屈嗪 盐酸盐物理化学性质

• 密度: 1.328g/cm3
• 分子式: C₁₁H₁₃ClN₄O₂
• 分子量: 268.70000
• 精确质量: 268.07300
• PSA: 76.14000
• LogP: 2.96870
• InChIKey: OMCOKCNIYWULQH-UHFFFAOYSA-N
• SMILES: CCOC(=O)NNc1nncc2ccccc12.Cl
• 储存条件: -20°C，密闭，干燥

托屈嗪 盐酸盐安全信息

• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): 36
• WGK德国: 3
• RTECS号: FE2778600
• 海关编码: 2933990090

托屈嗪 盐酸盐海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

托屈嗪 盐酸盐靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree... 来源：824 靶标：N/A External Id：P53600

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce... 来源：824 靶标：N/A External Id：P53MS958

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary 来源：824 External Id：P53MS482

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托屈嗪 盐酸盐英文别名

• 3-Phthalazin-1-yl-carbazidsaeure-aethylester,Hydrochlorid
• Todralazine HCl
• Apirachol
• Ecarazine
• Todralazine hydrochloride
• 3-phthalazin-1-yl-carbazic acid ethyl ester,hydrochloride
• Ecarazine hydrochloride
• Binazine
• Binazin
• 621-BT hydrochloride