甲醇中喷布特罗溶液标准物质

更新时间：2025-08-21 10:04:41

甲醇中喷布特罗溶液标准物质结构式	常用名	甲醇中喷布特罗溶液标准物质	英文名	Penbutolol sulfate
	CAS号	38363-32-5	分子量	340.47
	密度	N/A	沸点	438.2ºC at 760mmHg
	分子式	C₁₈H₂₉NO_2.1/₂H₂O₄S	熔点	216-218℃ (Decomposition)
	MSDS	N/A	闪点	218.8ºC

甲醇中喷布特罗溶液标准物质用途

Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。

中文名	硫酸喷布洛尔
英文名	Penbutolol sulfate
中文别名	喷布洛尔硫酸盐
英文别名	更多

描述	Penbutolol硫酸盐能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于治疗高血压。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体研究领域 >> 心血管疾病

沸点	438.2ºC at 760mmHg
熔点	216-218℃ (Decomposition)
分子式	C₁₈H₂₉NO_2.1/₂H₂O₄S
分子量	340.47
闪点	218.8ºC
PSA	41.49000
LogP	3.86290
InChIKey	FEDSNBHHWZEYTP-ZFQYHYQMSA-N
SMILES	CC(C)(C)NCC(O)COc1ccccc1C1CCCC1.CC(C)(C)NCC(O)COc1ccccc1C1CCCC1.O=S(=O)(O)O
储存条件	2-8°C

甲醇中喷布特罗溶液标准物质毒性英文版

危害码 (欧洲)	Xn
危险品运输编码	NONH for all modes of transport

5-HT receptor subtypes involved in the spinal antinociceptive effect of acetaminophen in rats.

Eur. J. Pharmacol. 432(1) , 1-7, (2001)

The present study was designed to investigate which subtype of spinal 5-HT receptors were involved in acetaminophen-induced antinociception using the paw-pressure test. Propacetamol (prodrug of acetam...

Autoreceptors remain functional after prolonged treatment with a serotonin reuptake inhibitor.

Brain Res. 835(2) , 224-8, (1999)

Serotonin (5-hydroxytryptamine, 5-HT) autoreceptors may desensitize during prolonged administration of antidepressant drugs. If autoreceptors desensitize, their inhibitory influence on extracellular 5...

Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain.

J. Neurochem. 75(2) , 755-62, (2000)

There is considerable interest in the use of drugs that selectively block presynaptic (somatodendritic) serotonin 5-HT(1A) receptors for the adjunctive treatment of major depressive disorder. The 5-HT...

实验名称：qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signa...
来源：824
靶标：AR protein [Homo sapiens]
External Id：MDAN535

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
来源：NCGC
靶标：TDP1 protein [Homo sapiens]
External Id：TDP1100

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
来源：NCGC
靶标：TDP1 protein [Homo sapiens]
External Id：TDP1101

实验名称：qHTS assay to identify small molecule antagonists of the androgen receptor (AR) sign...
来源：824
靶标：N/A
External Id：MDAV150

实验名称：qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cel...
来源：824
靶标：RecName: Full=ATPase family AAA domain-containing protein 5; AltName: Full=Chromosome fragility-associated gene 1 protein
External Id：ELG271

实验名称：Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay
来源：24386
靶标：N/A
External Id：Sarm1 Tir NADase inhibitors screen

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, green ...
来源：NCGC
靶标：N/A
External Id：Ebola screen1_EM141217_green

实验名称：qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
来源：824
靶标：thyroid hormone receptor beta isoform 2 [Rattus norvegicus]
External Id：TRN186

实验名称：qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
来源：824
靶标：N/A
External Id：TRV455

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, ratio ...
来源：NCGC
靶标：N/A
External Id：Ebola screen1_EM141217_ratio

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