尾叶香茶菜戊素

• 常用名: 尾叶香茶菜戊素
• 英文名: Kamebanin
• CAS号: 39388-57-3
• 分子量: 334.45
• 密度: 1.2±0.1 g/cm3
• 沸点: 514.0±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₀O₄
• 熔点: N/A
• 闪点: 278.8±26.6 °C

尾叶香茶菜戊素用途

Kamebanin可从卫叶Isodon weisiensis C.Y.Wu的叶片中分离得到。Kamebanin具有抗增殖活性,可用于癌症研究[1]。

尾叶香茶菜戊素名称

• 中文名: 尾叶香茶菜戊素
• 英文名: (1α,5β,7α,8α,9β,10α,13α,14R)-1,7,14-Trihydroxykaur-16-en-15-one

尾叶香茶菜戊素生物活性

• 描述: Kamebanin可从卫叶Isodon weisiensis C.Y.Wu的叶片中分离得到。Kamebanin具有抗增殖活性,可用于癌症研究[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Ding L, et al. Isolation, characterization and crystal structure of cytotoxic ent-kaurane diterpenoids from Isodon weisiensis CY Wu[J]. Zeitschrift für Naturforschung B, 2005, 60(7): 805-810.

尾叶香茶菜戊素物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 514.0±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₀O₄
• 分子量: 334.45
• 闪点: 278.8±26.6 °C
• 精确质量: 334.214417
• PSA: 77.76000
• LogP: 1.46
• InChIKey: VSDVMWBRICFVRW-BIGDWJEQSA-N
• SMILES: C=C1C(=O)C23C(O)CC4C(C)(C)CCC(O)C4(C)C2CCC1C3O
• 外观性状: 粉末
• 蒸汽压: 0.0±3.0 mmHg at 25°C
• 折射率: 1.582
• 储存条件: 2-8℃，干燥，密闭

尾叶香茶菜戊素安全信息

• 危害码 (欧洲): Xi

尾叶香茶菜戊素靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：HTS to identify inhibitors of Caspase inhibitor (zVAD) Induced Cell Death in L929 Cel... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：N/A External Id：HTS to identify inhibitors of Caspase Inhibitor (zVAD) Induced Cell Death in L929 Cells: Confirmation Assays, MH81266

实验名称：HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules: Confir... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：N/A External Id：HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules: Confirmation Assay, R21NS057026

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

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尾叶香茶菜戊素英文别名

• (1α,5β,7α,8α,9β,10α,13α,14R)-1,7,14-Trihydroxykaur-16-en-15-one