4-过氧化氢异环磷酰胺

• 常用名: 4-过氧化氢异环磷酰胺
• 英文名: 2H-1,3,2-Oxazaphosphorin-2-amine,N,3-bis(2-chloroethyl)tetrahydro-4-hydroperoxy-, 2-oxide
• CAS号: 39800-28-7
• 分子量: 293.08
• 密度: 1.46g/cm3
• 沸点: 419.9ºC at 760mmHg
• 分子式: C₇H₁₅Cl₂N₂O₄P
• 熔点: N/A
• 闪点: 207.8ºC

4-过氧化氢异环磷酰胺用途

4-过氧化氢一磷酰胺是一种可以穿透血脑屏障(BBB)的抗癌剂[1]。

4-过氧化氢异环磷酰胺名称

• 中文名: 4-过氧化氢异环磷酰胺
• 英文名: 4-hydroperoxyifosfamide

4-过氧化氢异环磷酰胺生物活性

• 描述: 4-过氧化氢一磷酰胺是一种可以穿透血脑屏障(BBB)的抗癌剂[1]。
• 相关类别:
  研究领域 >> 癌症
• 参考文献:

  [1]. Ishimoto TM, et al. Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli. Pharmacogenetics. 2002 Oct;12(7):543-53.

4-过氧化氢异环磷酰胺物理化学性质

• 密度: 1.46g/cm3
• 沸点: 419.9ºC at 760mmHg
• 分子式: C₇H₁₅Cl₂N₂O₄P
• 分子量: 293.08
• 闪点: 207.8ºC
• 精确质量: 292.01500
• PSA: 80.84000
• LogP: 2.02850
• InChIKey: YGZIWEZFFBPCLN-UHFFFAOYSA-N
• SMILES: O=P1(NCCCl)OCCC(OO)N1CCCl
• 折射率: 1.525

4-过氧化氢异环磷酰胺毒性和生态

4-过氧化氢异环磷酰胺靶点实验

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实验名称：qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Prima... 来源：NCGC 靶标：apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] External Id：AMA1100

实验名称：Antileukemic activity against mouse L1210 cells allografted in ip dosed BDF1 mouse as... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL3257529

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：abhydrolase domain-containing protein 4 isoform 1 [Mus musculus] External Id：ABHD4_INH_FP_1536_1X%INH PRUN

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4-过氧化氢异环磷酰胺英文别名

• Hydroperoxyisophosphamide
• 4-Hydroperoxyisophosphamid
• 4-Hydroperoxyifosfamid
• asta6760
• 4-hydroperoxyisophosphamide