FPL 55712

• 常用名: FPL 55712
• 英文名: FPL 55712
• CAS号: 40785-97-5
• 分子量: 498.52
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₃₀O₉
• 熔点: N/A
• 闪点: N/A

FPL 55712名称

• 英文名: 7-[3-(4-acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid.

FPL 55712生物活性

• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 白三烯受体
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. O'Donnell M, et al. Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions. 1984 Jan;14(1):43-8.

  [2]. Folkerts G, Vet al. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur J Pharmacol. 1995 Oct 16;285(2):R1-2.

  [3]. Chand N. FPL 55712 -- an antagonist of slow reacting substance of anaphylaxis (SRS-A): a review. Agents Actions. 1979 Jun;9(2):133-40.

FPL 55712物理化学性质

• 分子式: C₂₇H₃₀O₉
• 分子量: 498.52
• 精确质量: 498.18900
• PSA: 143.50000
• LogP: 4.12310
• InChIKey: LMQBMWHHGVZWMR-UHFFFAOYSA-N
• SMILES: CCCc1c(OCC(O)COc2ccc3c(=O)cc(C(=O)O)oc3c2CCC)ccc(C(C)=O)c1O

FPL 55712靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Inhibition of leukotriene-induced contractions of peripheral guinea pig lung strip 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL686878

实验名称：Antiallergic activity against ip dosed passive peritoneal anaphylaxis rat model asses... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3232127

实验名称：Antagonism of slow reacting substance of anaphylaxis-induced effect in guinea pig ile... 来源：ChEMBL 靶标：Ileum External Id：CHEMBL3232126

实验名称：Compound was tested for LTD4 induced guinea pig trachea contraction 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL691149

实验名称：Duration of action of leukotriene D4 as time for inhibition to decrease to 40%, compo... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL687492

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell... 来源：ChEMBL 靶标：Bile salt export pump External Id：CHEMBL4017550

实验名称：Duration of action of leukotriene D4 as time for inhibition to decrease to 40%, when ... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL687494

实验名称：Inhibition of leukotriene D4 induced bronchoconstriction in anesthetized guinea pigs ... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL684587

共90条，当前第1页，共9页

1

2

3

4

5

FPL 55712英文别名

• 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-benzopyran-2-carboxylic acid
• FPL-55712
• 7-[3-(4-acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxy-propoxy]-4-oxo-8-propyl-4H-chromene-2-carboxylic acid
• 8-propyl-7-[3-(4-acetyl-3-hydroxy-2-n-propylphenoxy)-2-hydroxypropoxy]-4-oxo-4H-1-benzopyran-2-carboxylic acid
• 7-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid
• 4,4-Pentamethylenepiperidine hydrochloride