Hannokinol

• 常用名: Hannokinol
• 英文名: Hannokinol
• CAS号: 408324-76-5
• 分子量: 316.39
• 密度: 1.2±0.1 g/cm3
• 沸点: 570.2±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₄O₄
• 熔点: N/A
• 闪点: 266.9±24.7 °C

Hannokinol用途

(+)-Hannokinol可从姜科(AMOMUM TSAO-KO)果实中分离得到。(+)-Hannokinol抑制脂多糖诱导的BV2小胶质细胞一氧化氮的产生[1]。

Hannokinol名称

• 英文名: (3R,5R)-1,7-Bis(4-hydroxyphenyl)-3,5-heptanediol

Hannokinol生物活性

• 描述: (+)-Hannokinol可从姜科(AMOMUM TSAO-KO)果实中分离得到。(+)-Hannokinol抑制脂多糖诱导的BV2小胶质细胞一氧化氮的产生[1]。
• 相关类别:
  信号通路 >> 免疫及炎症 >> 一氧化氮合酶
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Lee KY, et al. Inhibitory constituents of lipopolysaccharide-induced nitric oxide production in BV2 microglia isolated from Amomum tsao-ko. Planta Med. 2008 Jun;74(8):867-9.

Hannokinol物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 570.2±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₄O₄
• 分子量: 316.39
• 闪点: 266.9±24.7 °C
• 精确质量: 316.167450
• LogP: 2.32
• InChIKey: GZVIQGVWSNEONZ-RTBURBONSA-N
• SMILES: Oc1ccc(CCC(O)CC(O)CCc2ccc(O)cc2)cc1
• 外观性状: 粉末
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.616
• 储存条件: 2-8℃

Hannokinol靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse B16-4A5 cells assessed as cell viability at 10 uM after 70... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2427905

实验名称：Inhibition of mushroom tyrosinase at 10 uM 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL2427904

实验名称：Cytoprotective activity against sodium taurocholate-induced necrosis in Balb/C mouse ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3999804

实验名称：Cytotoxicity against human HL60 cells after 72 hrs by MTT assay 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1021668

实验名称：Cytotoxicity against HGF by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL1021670

实验名称：Cytotoxicity against human HSC2 cells by MTT assay 来源：ChEMBL 靶标：HSC-2 External Id：CHEMBL1021669

实验名称：Inhibition of differentiation of mouse 3T3L1 cells assessed as lipid accumulation at ... 来源：ChEMBL 靶标：3T3-L1 External Id：CHEMBL2352643

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427909

实验名称：Cytotoxicity against mouse 3T3L1 cells at 100 uM 来源：ChEMBL 靶标：3T3-L1 External Id：CHEMBL2352637

实验名称：Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophyllin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2427908

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Hannokinol英文别名

• (3R,5R)-1,7-Bis(4-hydroxyphenyl)-3,5-heptanediol