Isoandrographolide

• 常用名: Isoandrographolide
• 英文名: Isoandrographolide
• CAS号: 4176-96-9
• 分子量: 350.45
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₃₀O₅
• 熔点: N/A
• 闪点: N/A

Isoandrographolide用途

异穿心莲内酯具有诱导细胞分化和保肝作用。异穿心莲内酯抑制小鼠NLRP3炎性体激活并减轻矽肺[1][2]。

Isoandrographolide名称

• 英文名: Isoandrographolide

Isoandrographolide生物活性

• 描述: 异穿心莲内酯具有诱导细胞分化和保肝作用。异穿心莲内酯抑制小鼠NLRP3炎性体激活并减轻矽肺[1][2]。
• 相关类别:
  信号通路 >> 免疫及炎症 >> NOD样受体(NLR)
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. T Matsuda, et al. Cell differentiation-inducing diterpenes from Andrographis paniculata Nees. Chem Pharm Bull (Tokyo). 1994 Jun;42(6):1216-25.

  [2]. Zhe Song, et al. Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice. Int Immunopharmacol. 2022 Apr;105:108539.

Isoandrographolide物理化学性质

• 分子式: C₂₀H₃₀O₅
• 分子量: 350.45

Isoandrographolide靶点实验

查看更多实验

实验名称：Antimicrobial activity against Staphylococcus aureus at 10 ug/ml by disk diffusion as... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL972257

实验名称：Antimicrobial activity against Bacillus subtilis at 10 ug/ml by disk diffusion assay 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL972256

实验名称：Antimicrobial activity against Micrococcus luteus at 10 ug/ml by disk diffusion assay 来源：ChEMBL 靶标：Micrococcus luteus External Id：CHEMBL973154

实验名称：Antimicrobial activity against Escherichia coli at 10 ug/ml by disk diffusion assay 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL972258

实验名称：Antimicrobial activity against Candida sake at 10 ug/ml by disk diffusion assay 来源：ChEMBL 靶标：[Candida] sake External Id：CHEMBL973156

实验名称：Antimicrobial activity against Candida albicans at 10 ug/ml by disk diffusion assay 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL973155

实验名称：Antimicrobial activity against Aspergillus niger at 10 ug/ml by disk diffusion assay 来源：ChEMBL 靶标：Aspergillus niger External Id：CHEMBL973157

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