H-Val-Pro-Leu-Ser-Leu-Tyr-Ser-Gly-OH trifluoroacetate salt

• 常用名: H-Val-Pro-Leu-Ser-Leu-Tyr-Ser-Gly-OH trifluoroacetate salt
• 英文名: H-Val-Pro-Leu-Ser-Leu-Tyr-Ser-Gly-OH trifluoroacetate salt
• CAS号: 425632-67-3
• 分子量: 834.96
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₉H₆₂N₈O₁₂
• 熔点: N/A
• 闪点: N/A

用途

VPLSLYSG是一种可被基质金属蛋白酶-9(MMP-9)、MMP-1和MMP-2降解的八肽。VPLSLYSG在MMP底物中具有潜在的应用[1][2][3]。

名称

• 英文名: H-Val-Pro-Leu-Ser-Leu-Tyr-Ser-Gly-OH trifluoroacetate salt

生物活性

• 描述: VPLSLYSG是一种可被基质金属蛋白酶-9(MMP-9)、MMP-1和MMP-2降解的八肽。VPLSLYSG在MMP底物中具有潜在的应用[1][2][3]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 代谢酶/蛋白酶 >> MMP
• 参考文献:

  [1]. Suzuki H, et al. Accurate targeting of activated macrophages based on synergistic activation of functional molecules uptake by scavenger receptor and matrix metalloproteinase. ACS Chem Biol. 2008 Aug 15;3(8):471-9.

  [2]. Patterson J, et al. Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. Biomaterials. 2010 Oct;31(30):7836-45.

  [3]. Wieduwild R, et al. Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions. Biomaterials. 2018 Oct;180:253-264.

物理化学性质

• 分子式: C₃₉H₆₂N₈O₁₂
• 分子量: 834.96
• InChIKey: BBIPYBISAHJFBL-TYXFFDKISA-N
• SMILES: CC(C)CC(NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(N)C(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CO)C(=O)NCC(=O)O.O=C(O)C(F)(F)F