金缕梅单宁

更新时间:2024-01-10 11:46:28

金缕梅单宁结构式
金缕梅单宁结构式
品牌特惠专场
常用名 金缕梅单宁 英文名 Hamamelitannin
CAS号 469-32-9 分子量 484.364
密度 1.8±0.1 g/cm3 沸点 941.7±65.0 °C at 760 mmHg
分子式 C20H20O14 熔点 145-147ºC
MSDS 中文版 美版 闪点 329.0±27.8 °C

 金缕梅单宁用途


Hamamelitannin 是从 Hamamelis virginiana 树皮中提取的多酚,是一种群体感应 (QS) 抑制剂。Hamamelitannin 通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。

 金缕梅单宁名称

中文名 金缕梅单宁
英文名 hamamelitannin
中文别名 金缕梅丹宁酸
英文别名 更多

 金缕梅单宁生物活性

描述 Hamamelitannin 是从 Hamamelis virginiana 树皮中提取的多酚,是一种群体感应 (QS) 抑制剂。Hamamelitannin 通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。
相关类别
体外研究 金缕梅素显示对结肠癌细胞特异的细胞毒活性〔3〕。
参考文献

[1]. Kiran MD, et al. Discovery of a quorum-sensing inhibitor of drug-resistant staphylococcal infections by structure-based virtual screening. Mol Pharmacol. 2008 May;73(5):1578-86.

[2]. Cobrado L, et al. In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections. J Antimicrob Chemother. 2013 Jan;68(1):126-30.

[3]. Sánchez-Tena S, et al. Hamamelitannin displays specific cytotoxic activity against colon cancer cells. J Nat Prod. 2012 Jan 27;75(1):26-33.

 金缕梅单宁物理化学性质

密度 1.8±0.1 g/cm3
沸点 941.7±65.0 °C at 760 mmHg
熔点 145-147ºC
分子式 C20H20O14
分子量 484.364
闪点 329.0±27.8 °C
精确质量 484.085297
PSA 243.90000
LogP 2.91
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.746
储存条件 2-8°C,密封,干燥

 金缕梅单宁安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
WGK德国 3

 金缕梅单宁文献14

更多文献
Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo.

Antimicrob. Agents Chemother. 55 , 2655-2661, (2011)

Although the exact role of quorum sensing (QS) in various stages of biofilm formation, maturation, and dispersal and in biofilm resistance is not entirely clear, the use of QS inhibitors (QSI) has bee...

Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells.

J. Nat. Prod. 75 , 26-33, (2012)

Hamamelis virginiana (witch hazel) bark is a rich source of condensed and hydrolyzable tannins reported to exert a protective action against colon cancer. The present study characterizes different wit...

Cerium, chitosan and hamamelitannin as novel biofilm inhibitors?

J. Antimicrob. Chemother. 67 , 1159-62, (2012)

The colonization of indwelling medical devices and subsequent biofilm formation represents a global challenge since it promotes the persistence of infection and contributes to antimicrobial resistance...

 金缕梅单宁英文别名

HAMAMELOFURANOSE 2',5-DIGALLATE
2',5-DigalloylhaMaMelofuranose
2,3-Digalloylglucose
[(2R,3R,4R)-3,4,5-Trihydroxytetrahydrofuran-2,4-diyl]bis(methylen)bis(3,4,5-trihydroxybenzoat)
2-C-[[(3,4,5-Trihydroxybenzoyl)oxy]methyl]-D-ribofuranose 5-(3,4,5-trihydroxybenzoate)
Bis(3,4,5-trihydroxybenzoate) de [(2R,3R,4R)-3,4,5-trihydroxytétrahydrofurane-2,4-diyl]bis(méthylène)
2',5-digalloylhamamelose
hamamelitanin
Hamamelitannin
[(2R,3R,4R)-3,4,5-Trihydroxytetrahydrofuran-2,4-diyl]bis(methylene) bis(3,4,5-trihydroxybenzoate)
O5-Galloyl-2-galloyloxymethyl-D-ribose
5-O-(3,4,5-Trihydroxybenzoyl)-2-C-{[(3,4,5-trihydroxybenzoyl)oxy]methyl}-D-ribofuranose
D-Ribofuranose, 2-C-[[(3,4,5-trihydroxybenzoyl)oxy]methyl]-, 5-(3,4,5-trihydroxybenzoate)
2-C-(Hydroxymethyl)-D-ribofuranose 2',5-Digallate
品牌现货直购
推荐供应商:


查看所有供应商和价格请点击:

金缕梅单宁生产厂家

金缕梅单宁价格