花姜酮

更新时间：2024-01-04 18:14:41

花姜酮结构式	常用名	花姜酮	英文名	zerumbone
	CAS号	471-05-6	分子量	218.335
	密度	0.9±0.1 g/cm3	沸点	321.6±42.0 °C at 760 mmHg
	分子式	C₁₅H₂₂O	熔点	67-69℃
	MSDS	中文版美版	闪点	133.9±22.8 °C
	符号	GHS07, GHS09	信号词	Warning

花姜酮用途

Zerumbone 是从Zingiber zerumbet Smith 的根茎中分离出来的单环倍半萜烯化合物。Zerumbone 有效抑制Epstein-Barr 病毒的激活,IC50 为 0.14 mM。Zerumbone 具有抗癌,抗氧化,抗炎,抗增殖的作用。

中文名	花薑酮
英文名	zerumbone
中文别名	花姜酮
英文别名	更多

描述	Zerumbone 是从Zingiber zerumbet Smith 的根茎中分离出来的单环倍半萜烯化合物。Zerumbone 有效抑制Epstein-Barr 病毒的激活,IC50 为 0.14 mM。Zerumbone 具有抗癌,抗氧化,抗炎,抗增殖的作用。
相关类别	信号通路 >> 抗感染 >> HSV 研究领域 >> 感染
参考文献	[1]. Murakami A, et al. Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation. Biosci Biotechnol Biochem. 1999 Oct;63(10):1811-2. [2]. Kalantari K, et al. A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extractionfrom Ginger Rhizomes. Molecules. 2017 Sep 30;22(10).

描述

相关类别

信号通路 >> 抗感染 >> HSV

研究领域 >> 感染

参考文献

[1]. Murakami A, et al. Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation. Biosci Biotechnol Biochem. 1999 Oct;63(10):1811-2.

[2]. Kalantari K, et al. A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extractionfrom Ginger Rhizomes. Molecules. 2017 Sep 30;22(10).

密度	0.9±0.1 g/cm3
沸点	321.6±42.0 °C at 760 mmHg
熔点	67-69℃
分子式	C₁₅H₂₂O
分子量	218.335
闪点	133.9±22.8 °C
精确质量	218.167068
PSA	17.07000
LogP	5.34
蒸汽压	0.0±0.7 mmHg at 25°C
折射率	1.468
储存条件	2-8℃

符号	GHS07, GHS09
信号词	Warning
危害声明	H317-H400
警示性声明	P273-P280
危害码 (欧洲)	Xn
风险声明 (欧洲)	43-50
安全声明 (欧洲)	36/37-60-61
危险品运输编码	UN 3077 9 / PGIII

Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis.

Cell. Mol. Life Sci. 68(6) , 1033-40, (2011)

Plant cytochrome P450s are involved in the biosynthesis of various classes of secondary metabolites. To elucidate the biosynthesis of zerumbone, a sesquiterpenoid with multiple potential anticancer pr...

Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance.

Int. J. Radiat. Oncol. Biol. Phys. 79(4) , 1196-205, (2011)

HSP27 or HSP25 negatively regulates apoptosis pathways after radiation or chemotherapeutic agents. Abrogation of HSP27 function may be a candidate target for overcoming radio- and chemoresistance.Zeru...

Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages.

Arch. Toxicol. 84(12) , 957-66, (2010)

To assess the effectiveness of selected food phytochemicals in reducing the toxic effects of the environmental toxicants, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and p,p'-DDT (DDT), we tested the p...

(2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one

(2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trien-1-one

2,6,10-Cycloundecatrien-1-one, 2,6,9,9-tetramethyl-, (2E,6E,10E)-

ZERUMBONE ((2E,6E,10E)-2,6,9,9-TETRAMETHYLCYCLOUNDECA-2,6,10-TRIEN-1-ONE)

zerumbone