莪术醇; 姜黄醇

• 常用名: 莪术醇; 姜黄醇
• 英文名: Curcumol
• CAS号: 4871-97-0
• 分子量: 236.350
• 密度: 1.1±0.1 g/cm3
• 沸点: 334.5±42.0 °C at 760 mmHg
• 分子式: C₁₅H₂₄O₂
• 熔点: 141-142ºC
• 闪点: 134.7±22.1 °C

莪术醇; 姜黄醇用途

莪术醇(Curcumol)是一抗癌活性的倍半萜醇天然化合物。

莪术醇; 姜黄醇名称

• 中文名: 莪术醇
• 英文名: Curcumol
• 中文别名: 莪术醇.姜黄醇.莪黄醇.姜黄环氧醇 | 姜黄醇

莪术醇; 姜黄醇生物活性

• 描述: 莪术醇(Curcumol)是一抗癌活性的倍半萜醇天然化合物。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 癌症
  天然产物 >> 萜类化合物和糖苷
• 参考文献:

  [1]. Tang QL, et al. Curcumol induces apoptosis in SPC-A-1 human lung adenocarcinoma cells and displays anti-neoplastic effects in tumor bearing mice. Asian Pac J Cancer Prev. 2015;16(6):2307-12.

  [2]. Chen G, et al. Curcumol induces HSC-T6 cell death through suppression of Bcl-2: involvement of PI3K and NF-κB pathways. Eur J Pharm Sci. 2014 Dec 18;65:21-8.

  [3]. Yu M, et al. Curcumol suppresses RANKL-induced osteoclast formation by attenuating the JNK signaling pathway. Biochem Biophys Res Commun. 2014 May 2;447(2):364-70.

莪术醇; 姜黄醇物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 334.5±42.0 °C at 760 mmHg
• 熔点: 141-142ºC
• 分子式: C₁₅H₂₄O₂
• 分子量: 236.350
• 闪点: 134.7±22.1 °C
• 精确质量: 236.177628
• PSA: 29.46000
• LogP: 3.25
• InChIKey: QRMPRVXWPCLVNI-YYFQZIEXSA-N
• SMILES: C=C1CC2(O)OC3(CC2C(C)C)C(C)CCC13
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.526
• 储存条件: 室温

莪术醇; 姜黄醇安全信息

• 危害码 (欧洲): Xi
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 29321900

莪术醇; 姜黄醇靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line SW-13 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-SW13-72hr

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line NCI-H295R 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-H295R-72hr

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：Enzymatic assay of human HDAC6 with custom peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808150

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

实验名称：qHTS assay to identify novel small-molecules to repurpose for Merkel cell carcinoma t... 来源：NCGC 靶标：N/A External Id：MCC011

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莪术醇; 姜黄醇英文别名

• (3S,3aS,5S,8aS)-3-methyl-8-methylidene-5-(propan-2-yl)octahydro-6H-3a,6-epoxyazulen-6-ol
• (3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol
• (1S,2S,5S,9S)-9-Isopropyl-2-methyl-6-methylene-11-oxatricyclo[6.2.1.0]undecan-8-ol