BETA-雌二醇 3-硫酸钠盐

更新时间：2025-08-25 22:09:16

BETA-雌二醇 3-硫酸钠盐结构式	常用名	BETA-雌二醇 3-硫酸钠盐	英文名	17-Beta-Estradiol-3-O-Sulfate Sodium
	CAS号	4999-79-5	分子量	374.427
	密度	N/A	沸点	N/A
	分子式	C₁₈H₂₃NaO₅S	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS07, GHS08	信号词	Warning

BETA-雌二醇 3-硫酸钠盐用途

17β-雌二醇硫酸盐(钠),也称为β-雌二醇3-硫酸盐钠盐,是一种神经活性类固醇[1][2]。

中文名	BETA-雌二醇 3-硫酸钠盐
英文名	1,3,5[10]-estratriene-3,17beta-diol 3-sulfate sodium salt
英文别名	更多

描述	17β-雌二醇硫酸盐(钠),也称为β-雌二醇3-硫酸盐钠盐,是一种神经活性类固醇[1][2]。
相关类别	信号通路 >> 跨膜转运 >> GABA受体研究领域 >> 神经疾病信号通路 >> 神经信号通路 >> GABA受体
体外研究	17β-硫酸雌二醇(钠)是一种神经活性类固醇[1][2]。
参考文献	[1]. Li W, et al. Neuroactive steroids and human recombinant rho1 GABAC receptors. J Pharmacol Exp Ther. 2007;323(1):236-247. [2]. Schneider C, et al. A novel enzyme-linked immunosorbent assay for ethynylestradiol using a long-chain biotinylated EE2 derivative. Steroids. 2004;69(4):245-253.

分子式	C₁₈H₂₃NaO₅S
分子量	374.427
精确质量	374.116394
PSA	95.04000
LogP	3.82340
InChIKey	LMJQCTISQYSLPF-CMZLOHJFSA-M
SMILES	CC12CCC3c4ccc(OS(=O)(=O)[O-])cc4CCC3C1CCC2O.[Na+]

符号	GHS07, GHS08
信号词	Warning
危害声明	H302-H332-H351
警示性声明	P281
个人防护装备	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
危害码 (欧洲)	Xn: Harmful;
风险声明 (欧洲)	R20/21/22
安全声明 (欧洲)	22-36
危险品运输编码	NONH for all modes of transport

雌二醇

50-28-2

叔丁醇钠

865-48-5

~90%

BETA-雌二醇 3-硫酸钠盐

4999-79-5

文献：WYETH Patent: US2008/194533 A1, 2008 ; Location in patent: Page/Page column 15-16 ;

雌二醇

50-28-2

1-nitro-4-sulfo...

1080-04-2

~55%

对硝基苯酚

100-02-7

BETA-雌二醇 3-硫酸钠盐

4999-79-5

文献：Van Der Horst, Michael A.; Van Lieshout, Johan F. T.; Bury, Aleksandra; Hartog, Aloysius F.; Wever, Ron Advanced Synthesis and Catalysis, 2012 , vol. 354, # 18 p. 3501 - 3508

BETA-雌二醇 3-硫酸钠盐上游产品 3
CAS号50-28-2 雌二醇 CAS号865-48-5 叔丁醇钠 CAS号1080-04-2 1-nitro-4-sulfo...
BETA-雌二醇 3-硫酸钠盐下游产品 0

Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate.

J. Steroid Biochem. Mol. Biol. 96(5) , 367-74, (2005)

Using recombinant sulfotransferases (SULTs) expressed in E. coli, beta-estradiol (E2) sulfonation was examined to determine which SULT enzyme is responsible for producing E2-17-sulfate (E2-17-S). SULT...

Steroid sulphate secretion by the human ovary in vitro: influence of gonadotrophins, cyclofenil and clomiphene.

J. Steroid Biochem. 13(12) , 1401-6, (1980)

[Evidence, in vitro, of estrone and estradiol-17 beta 3-sulfoconjugate hydrolysis in the uterus of pregnant guinea pigs].

C. R. Seances. Acad. Sci. III. 292(9) , 609-12, (1981)

The metabolism, in vitro, of [6,7-3H]-oestrone-3-sulfate and [6,7-3H]-oestradiol-17beta-3-sulfate by the uteri of pregnant female Guinea-Pigs has been studied using 900 g supernatants. A hydrolysis of...

实验名称：Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimo...
来源：ChEMBL
靶标：Solute carrier organic anion transporter family member 1B1
External Id：CHEMBL3039488

实验名称：Inhibition of recombinant human CYP1B1 expressed in bacterial microsomes co-expressin...
来源：ChEMBL
靶标：Cytochrome P450 1B1
External Id：CHEMBL3877873

实验名称：Inhibition of full-length recombinant human CYP46A1 assessed as cholesterol hydroxyla...
来源：ChEMBL
靶标：Cholesterol 24-hydroxylase
External Id：CHEMBL4417815

实验名称：Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
来源：ChEMBL
靶标：Solute carrier organic anion transporter family member 1B3
External Id：CHEMBL3039491

共4条，当前第1页，共1页

b-Estradiol 3-sulfate sodium salt

Estra-1,3,5(10)-triene-3,17-diol, 3-(hydrogen sulfate), sodium salt, (17β)- (1:1)

17BETA-ESTRADIOL 3-SULFATE SODIUM

17BETA-ESTRADIOL 3-SULFATE SODIUM SALT

SODIUM 17B-ESTRADIOL 3-SULFATE

oestradiol 3-sulfate,sodium salt

17B-estradiol 3-sulfate sodium

17Beta-Estradiol 3-O-Sulfate Sodium Salt

Sodium (17β)-17-hydroxyestra-1,3,5(10)-trien-3-yl sulfate