1-(2,3-二(噻吩-2-基)喹啉-6-基)-3-(2-甲氧基乙基)脲

• 常用名: 1-(2,3-二(噻吩-2-基)喹啉-6-基)-3-(2-甲氧基乙基)脲
• 英文名: Ac-CoA Synthase Inhibitor1
• CAS号: 508186-14-9
• 分子量: 410.513
• 密度: 1.4±0.1 g/cm3
• 沸点: 539.3±50.0 °C at 760 mmHg
• 分子式: C₂₀H₁₈N₄O₂S₂
• 熔点: N/A
• 闪点: 280.0±30.1 °C

用途

Ac-CoA Synthase Inhibitor1 是一种抗病毒剂。

名称

• 中文名: Ac-CoA合成酶抑制剂1
• 英文名: ACSS2 inhibitor

生物活性

• 描述: Ac-CoA Synthase Inhibitor1 是一种抗病毒剂。
• 相关类别:
  信号通路 >> 抗感染 >> RSV
  研究领域 >> 感染
• 体外研究: Ac-CoA Synthase Inhibitor1抑制呼吸道合胞病毒(RSV)[1]。
• 参考文献:

  [1]. Bill Severson, et al. Anti-viral treatment and assay to screen for anti-viral agent. WO 2011097607 A1

物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 539.3±50.0 °C at 760 mmHg
• 分子式: C₂₀H₁₈N₄O₂S₂
• 分子量: 410.513
• 闪点: 280.0±30.1 °C
• 精确质量: 410.087128
• LogP: 3.71
• InChIKey: CTPVNWVUAGMHEJ-UHFFFAOYSA-N
• SMILES: COCCNC(=O)Nc1ccc2nc(-c3cccs3)c(-c3cccs3)nc2c1
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.691
• 储存条件: 室温，干燥

安全信息

• 危害码 (欧洲): Xi

靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti... 来源：The Scripps Research Institute Molecular Screening Center 靶标：caspase-3 preproprotein [Homo sapiens] External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

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英文别名

• 1-[2,3-Di(2-thienyl)-6-quinoxalinyl]-3-(2-methoxyethyl)urea
• Ac-CoA Synthase Inhibitor1