1,3,7-三羟基-9H-氧杂蒽-9-酮

• 常用名: 1,3,7-三羟基-9H-氧杂蒽-9-酮
• 英文名: Gentisein
• CAS号: 529-49-7
• 分子量: 244.20000
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₈O₅
• 熔点: N/A
• 闪点: N/A

1,3,7-三羟基-9H-氧杂蒽-9-酮用途

芒果苷的主要代谢物龙胆素(NSC 329491)显示出最有效的5-羟色胺摄取抑制,IC50值为4.7µM[1][2]。

1,3,7-三羟基-9H-氧杂蒽-9-酮名称

• 中文名: 1,3,7-三羟基-9H-氧杂蒽-9-酮
• 英文名: gentisein

1,3,7-三羟基-9H-氧杂蒽-9-酮生物活性

• 描述: 芒果苷的主要代谢物龙胆素(NSC 329491)显示出最有效的5-羟色胺摄取抑制,IC50值为4.7µM[1][2]。
• 相关类别:
  研究领域 >> 神经疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体
  信号通路 >> 神经信号通路 >> 5-HT受体
• 参考文献:

  [1]. Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798.

  [2]. Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2.

1,3,7-三羟基-9H-氧杂蒽-9-酮物理化学性质

• 分子式: C₁₃H₈O₅
• 分子量: 244.20000
• 精确质量: 244.03700
• PSA: 90.90000
• LogP: 2.06300
• InChIKey: JJUNZBRHHGLJQW-UHFFFAOYSA-N
• SMILES: O=c1c2cc(O)ccc2oc2cc(O)cc(O)c12

1,3,7-三羟基-9H-氧杂蒽-9-酮毒性和生态

1,3,7-三羟基-9H-氧杂蒽-9-酮安全信息

• 海关编码: 2932999099

1,3,7-三羟基-9H-氧杂蒽-9-酮海关

• 海关编码: 2932999099
• 中文概述: 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1,3,7-三羟基-9H-氧杂蒽-9-酮靶点实验

查看更多实验

实验名称：Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4316827

实验名称：Cytotoxicity against human Jurkat T cells assessed as NADH level after overnight incu... 来源：ChEMBL 靶标：Jurkat External Id：CHEMBL2021321

实验名称：Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL4034027

实验名称：HIV Enzyme Data 来源：NIAID 靶标：N/A External Id：HIV Enzyme Data

实验名称：Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4034028

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 after 20 to 22 hrs by brot... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL2021319

实验名称：Cytotoxicity against human HepG2 cells assessed as NADH level after overnight incubat... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL2021320

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as release of p-nit... 来源：ChEMBL 靶标：Alpha-glucosidase MAL12 External Id：CHEMBL5244965

实验名称：Inhibition of Influenza A virus H9N2 neuraminidase using 4-MU-NANA as substrate by fl... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL2034235

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1,3,7-三羟基-9H-氧杂蒽-9-酮英文别名

• Gentisein
• 9H-Xanthen-9-one,1,3,7-trihydroxy
• 1,3,7-trihydroxy-9H-xanthen-9-one
• 1,3,7-trihydroxy-xanthen-9-one
• Xanthen-9-one,1,3,7-trihydroxy
• 1,3,7-Trihydroxy-xanthen-9-on
• XANTHONE DERIV
• 1,3,7-trihydroxyxanthone
• 1,3,7-trihydroxyxanthen-9-one