(+)-4-[(R)-2-Hydroxy-3-methoxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one

• 常用名: (+)-4-[(R)-2-Hydroxy-3-methoxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one
• 英文名: (+)-4-[(R)-2-Hydroxy-3-methoxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one
• CAS号: 52939-12-5
• 分子量: 318.32
• 密度: 1.300±0.06 g/cm3
• 沸点: 504.3±50.0 °C
• 分子式: C₁₇H₁₈O₆
• 熔点: N/A
• 闪点: N/A

用途

(+)-甲氧代马齿苋素(化合物9)是一种天然化合物,对前列腺素E2的产生具有抑制作用[1]。

名称

• 英文名: oxypeucedanin methanolate

生物活性

• 描述: (+)-甲氧代马齿苋素(化合物9)是一种天然化合物,对前列腺素E2的产生具有抑制作用[1]。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Hyun Seung Ban, et al. Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production. Planta Med. 2003 May;69(5):408-12.

物理化学性质

• 密度: 1.300±0.06 g/cm3
• 沸点: 504.3±50.0 °C
• 分子式: C₁₇H₁₈O₆
• 分子量: 318.32
• 精确质量: 318.11000
• PSA: 82.04000
• LogP: 2.70390
• InChIKey: UHENVVIVPZCJOA-CQSZACIVSA-N
• SMILES: COC(C)(C)C(O)COc1c2ccoc2cc2oc(=O)ccc12
• 储存条件: 室温

靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Cytotoxicity against human PSN1 cells in DMEM measured after 24 hrs by WST8 assay 来源：ChEMBL 靶标：PSN1 External Id：CHEMBL4200163

实验名称：Cytotoxicity against human MIAPaCa2 cells in DMEM measured after 24 hrs by WST8 assay 来源：ChEMBL 靶标：MIA PaCa-2 External Id：CHEMBL4200162

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英文别名

• 4-((R)-2-Hydroxy-3-methoxy-3-methyl-butoxy)-furo[3,2-g]chromen-7-one
• tert-O-methyloxypeucedanin hydrate
• oxypeucedanin 3'-methyl ether
• 5-(2'-hydroxy-3'-methoxyisopentyloxy)psoralen