硫酸西索米星结构式
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常用名 | 硫酸西索米星 | 英文名 | Sisomycin Sulfate |
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CAS号 | 53179-09-2 | 分子量 | 692.72 | |
密度 | N/A | 沸点 | 676.6ºC at 760mmHg | |
分子式 | C19H37N5O7.5/2H2SO4 | 熔点 | 70-73ºC | |
MSDS | 中文版 美版 | 闪点 | 363ºC | |
符号 |
GHS07, GHS08 |
信号词 | Danger |
硫酸西索米星用途Sisomicin硫酸盐是一种氨基糖苷类抗生素。 |
中文名 | 硫酸西梭霉素 |
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英文名 | Sisomicin sulfate |
中文别名 | 硫酸西索紫苏 | 硫酸西梭米星/硫酸西索霉素 | 硫酸西梭米星 | 硫酸西索米星 |
英文别名 | 更多 |
沸点 | 676.6ºC at 760mmHg |
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熔点 | 70-73ºC |
分子式 | C19H37N5O7.5/2H2SO4 |
分子量 | 692.72 |
闪点 | 363ºC |
PSA | 842.34000 |
LogP | 0.82120 |
外观性状 | white to off-white |
储存条件 | 库房通风低温干燥,与食品原料分开存放 |
水溶解性 | H2O: soluble50mg/mL | Soluble in water |
符号 |
GHS07, GHS08 |
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信号词 | Danger |
危害声明 | H312 + H332-H360 |
警示性声明 | P201-P261-P280-P308 + P313 |
个人防护装备 | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
危害码 (欧洲) | T,Xi |
风险声明 (欧洲) | 61-20/21/22-36/37/38 |
安全声明 (欧洲) | 53-22-36/37/39-45-36-26 |
危险品运输编码 | NONH for all modes of transport |
WGK德国 | 3 |
RTECS号 | WK2288000 |
硫酸西索米星上游产品 0 | |
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硫酸西索米星下游产品 1 | |
Determination of equilibrium constant of amino carbamate adduct formation in sisomicin by a high pH based high performance liquid chromatography.
J. Pharm. Biomed. Anal. 111 , 126-30, (2015) Amino carbamate adduct formation from the amino group of an aminoglycoside and carbon dioxide has been postulated as a mechanism for reducing nephrotoxicity in the aminoglycoside class compounds. In t... |
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Biomimetic synthesis and structural refinement of the macrocyclic dimer aminoglycoside 66-40C--the remarkably selective self-condensation of a putative aldehyde intermediate in the submerged culture medium producing sisomicin.
Chem. Commun. (Camb.) 46(12) , 2013-5, (2010) Aminoglycoside 66-40C, an unprecedented 16-membered bis-azadiene macrocyclic natural product isolated from the Micromonospora producer of the antibiotic sisomicin, was synthesized following a biomimet... |
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Pharmacokinetics and safety of single and multiple doses of ACHN-490 injection administered intravenously in healthy subjects.
Antimicrob. Agents Chemother. 55(12) , 5874-80, (2011) ACHN-490 is an aminoglycoside with activity against multidrug-resistant pathogens, including those resistant to currently used aminoglycosides. Two randomized, double-blind, placebo-controlled clinica... |
Extramycin |
Siseptin |
Pathomycin |
sisomicin sulfate |
Antibiotic 66-40 sulfate |
O-3-Deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl(1®6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1®4)]-2-deoxy-D-streptamine Sulfate (2:5) (Salt) |
Sch 13475 sulfate |
(1S,2S,3R,4S,6R)-4,6-Diamino-3-{[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranoside sulfate (2:5) |
(2S-cis)-4-O-[3-Amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]-2-deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl]-D-streptamine Sulfate (2:5) (Salt) |
Mensiso |
Sisomycin sulfate |
Sisomin |
β-L-Arabinopyranoside, (1S,2S,3R,4S,6R)-4,6-diamino-3-[[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-, sulfate (2:5) (salt) |