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硫酸西索米星

更新时间:2024-01-03 11:14:59

硫酸西索米星结构式
硫酸西索米星结构式
品牌特惠专场
常用名 硫酸西索米星 英文名 Sisomycin Sulfate
CAS号 53179-09-2 分子量 692.72
密度 N/A 沸点 676.6ºC at 760mmHg
分子式 C19H37N5O7.5/2H2SO4 熔点 70-73ºC
MSDS 中文版 美版 闪点 363ºC
符号 GHS07 GHS08
GHS07, GHS08
信号词 Danger

 硫酸西索米星用途


Sisomicin硫酸盐是一种氨基糖苷类抗生素。

 硫酸西索米星名称

中文名 硫酸西梭霉素
英文名 Sisomicin sulfate
中文别名 硫酸西索紫苏 | 硫酸西梭米星/硫酸西索霉素 | 硫酸西梭米星 | 硫酸西索米星
英文别名 更多

 硫酸西索米星生物活性

描述 Sisomicin硫酸盐是一种氨基糖苷类抗生素。
相关类别

 硫酸西索米星物理化学性质

沸点 676.6ºC at 760mmHg
熔点 70-73ºC
分子式 C19H37N5O7.5/2H2SO4
分子量 692.72
闪点 363ºC
PSA 842.34000
LogP 0.82120
外观性状 white to off-white
储存条件 库房通风低温干燥,与食品原料分开存放
水溶解性 H2O: soluble50mg/mL | Soluble in water

 硫酸西索米星毒性和生态

 硫酸西索米星安全信息

符号 GHS07 GHS08
GHS07, GHS08
信号词 Danger
危害声明 H312 + H332-H360
警示性声明 P201-P261-P280-P308 + P313
个人防护装备 Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
危害码 (欧洲) T,Xi
风险声明 (欧洲) 61-20/21/22-36/37/38
安全声明 (欧洲) 53-22-36/37/39-45-36-26
危险品运输编码 NONH for all modes of transport
WGK德国 3
RTECS号 WK2288000

 硫酸西索米星上下游产品

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硫酸西索米星下游产品  1

 硫酸西索米星文献29

更多文献
Determination of equilibrium constant of amino carbamate adduct formation in sisomicin by a high pH based high performance liquid chromatography.

J. Pharm. Biomed. Anal. 111 , 126-30, (2015)

Amino carbamate adduct formation from the amino group of an aminoglycoside and carbon dioxide has been postulated as a mechanism for reducing nephrotoxicity in the aminoglycoside class compounds. In t...

Biomimetic synthesis and structural refinement of the macrocyclic dimer aminoglycoside 66-40C--the remarkably selective self-condensation of a putative aldehyde intermediate in the submerged culture medium producing sisomicin.

Chem. Commun. (Camb.) 46(12) , 2013-5, (2010)

Aminoglycoside 66-40C, an unprecedented 16-membered bis-azadiene macrocyclic natural product isolated from the Micromonospora producer of the antibiotic sisomicin, was synthesized following a biomimet...

Pharmacokinetics and safety of single and multiple doses of ACHN-490 injection administered intravenously in healthy subjects.

Antimicrob. Agents Chemother. 55(12) , 5874-80, (2011)

ACHN-490 is an aminoglycoside with activity against multidrug-resistant pathogens, including those resistant to currently used aminoglycosides. Two randomized, double-blind, placebo-controlled clinica...

 硫酸西索米星英文别名

Extramycin
Siseptin
Pathomycin
sisomicin sulfate
Antibiotic 66-40 sulfate
O-3-Deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl(1®6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1®4)]-2-deoxy-D-streptamine Sulfate (2:5) (Salt)
Sch 13475 sulfate
(1S,2S,3R,4S,6R)-4,6-Diamino-3-{[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranoside sulfate (2:5)
(2S-cis)-4-O-[3-Amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]-2-deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl]-D-streptamine Sulfate (2:5) (Salt)
Mensiso
Sisomycin sulfate
Sisomin
β-L-Arabinopyranoside, (1S,2S,3R,4S,6R)-4,6-diamino-3-[[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-, sulfate (2:5) (salt)
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