N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺

• 常用名: N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺
• 英文名: Carcinine hydrochloride salt
• CAS号: 56897-53-1
• 分子量: 182.22
• 密度: 1.2±0.1 g/cm3
• 沸点: 547.6±40.0 °C at 760 mmHg
• 分子式: C₈H₁₄N₄O
• 熔点: N/A
• 闪点: 285.0±27.3 °C

N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺用途

Alistin(Carcinine；β-丙氨酸组胺)是一种选择性组胺H3拮抗剂,对氧化应激小鼠的视网膜具有抗氧化活性和神经保护作用[1][2]。

N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺名称

• 中文名: N-2-[(4-1H-咪唑基)乙基]-3-氨基丙酰胺二盐酸盐
• 英文名: Carcinine Hydrochloride

N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺生物活性

• 描述: Alistin(Carcinine；β-丙氨酸组胺)是一种选择性组胺H3拮抗剂,对氧化应激小鼠的视网膜具有抗氧化活性和神经保护作用[1][2]。
• 相关类别:
  信号通路 >> 免疫及炎症 >> 组胺受体
  研究领域 >> 神经疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体
• 参考文献:

  [1]. Zhong Chen, et al. Pharmacological effects of carcinine on histaminergic neurons in the brain. Br J Pharmacol. 2004 Nov;143(5):573-80.

  [2]. Lea D Marchette, et al. Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina. Invest Ophthalmol Vis Sci. 2012 Jun 20;53(7):3572-83.

N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 547.6±40.0 °C at 760 mmHg
• 分子式: C₈H₁₄N₄O
• 分子量: 182.22
• 闪点: 285.0±27.3 °C
• 精确质量: 182.116760
• PSA: 87.29000
• LogP: -1.83
• InChIKey: ANRUJJLGVODXIK-UHFFFAOYSA-N
• SMILES: NCCC(=O)NCCc1cnc[nH]1
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.559
• 储存条件: 20°C

N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺安全信息

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36
• 海关编码: 2933290090

N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺海关

• 海关编码: 2933290090
• 中文概述: 2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺靶点实验

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N-(2-(1H-咪唑-5-基)乙基)-3-氨基丙酰胺英文别名

• carcinine
• N-[2-(1H-Imidazol-5-yl)ethyl]-β-alaninamide
• 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide