Norstictic Acid

• 常用名: Norstictic Acid
• 英文名: Norstictic Acid
• CAS号: 571-67-5
• 分子量: 372.28200
• 密度: 1.714g/cm3
• 沸点: 764.2ºC at 760mmHg
• 分子式: C₁₈H₁₂O₉
• 熔点: N/A
• 闪点: 283.7ºC

Norstictic Acid用途

去甲肾上腺素是一种有效的选择性异基因转录调节因子。去甲肾上腺素具有抗癌活性。去甲肾上腺素具有抗氧化活性和抗菌活性[1][2][3][4]。

Norstictic Acid名称

• 英文名: Norstictic acid

Norstictic Acid生物活性

• 描述: 去甲肾上腺素是一种有效的选择性异基因转录调节因子。去甲肾上腺素具有抗癌活性。去甲肾上腺素具有抗氧化活性和抗菌活性[1][2][3][4]。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 体外研究: 去甲肾上腺素能显著抑制TNBC MDA-MB-231细胞的增殖、迁移和侵袭,毒性较低[2]。
• 参考文献:

  [1]. Garlick JM, et al. Norstictic Acid Is a Selective Allosteric Transcriptional Regulator. J Am Chem Soc. 2021 Jun 30;143(25):9297-9302.

  [2]. Ebrahim HY, et al. Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C-Met. Phytother Res. 2016 Apr;30(4):557-66.

  [3]. Ranković B, et al. Biological activities of Toninia candida and Usnea barbata together with their norstictic acid and usnic acid constituents. Int J Mol Sci. 2012 Nov 12;13(11):14707-22.

  [4]. Tay T, et al. Evaluation of the antimicrobial activity of the acetone extract of the lichen Ramalina farinacea and its (+)-usnic acid, norstictic acid, and protocetraric acid constituents. Z Naturforsch C J Biosci. 2004 May-Jun;59(5-6):384-8.

Norstictic Acid物理化学性质

• 密度: 1.714g/cm3
• 沸点: 764.2ºC at 760mmHg
• 分子式: C₁₈H₁₂O₉
• 分子量: 372.28200
• 闪点: 283.7ºC
• 精确质量: 372.04800
• PSA: 139.59000
• LogP: 2.01330
• InChIKey: IEVVSJFLBYOUCJ-UHFFFAOYSA-N
• SMILES: Cc1cc(O)c(C=O)c2c1C(=O)Oc1c(C)c(O)c3c(c1O2)C(O)OC3=O
• 折射率: 1.747

Norstictic Acid靶点实验

查看更多实验

实验名称：Toxicity against neonate larval stage of Spodoptera littoralis fed with diet containi... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3057995

实验名称：Growth retarding activity against neonate larval stage of Spodoptera littoralis fed w... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3057468

实验名称：ERK5 transcriptional activity HTS 来源：24565 靶标：N/A External Id：ERK5 transcriptional activity-HTS

实验名称：Growth retarding activity against neonate larval stage of Spodoptera littoralis fed w... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3057471

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：Change in pupal weight of Spodoptera littoralis fed with diet containing compound at ... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3057474

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2mCherry

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Prolongation of duration of larval period in Spodoptera littoralis fed with diet cont... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3058021

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Norstictic Acid英文别名

• Bryopogonic acid