Uvaretin

• 常用名: Uvaretin
• 英文名: Uvaretin
• CAS号: 58449-06-2
• 分子量: 378.42
• 密度: 1.274g/cm3
• 沸点: 620.2ºC at 760 mmHg
• 分子式: C₂₃H₂₂O₅
• 熔点: N/A
• 闪点: 217.8ºC

Uvaretin用途

uvaretin和isouvaretin的混合物(HY-N10130)对枯草杆菌(EC50 8.7μM)和表皮葡萄球菌(IC50 7.9μM)具有显著的抗菌活性。

Uvaretin名称

• 英文名: 1-[2,4-dihydroxy-3-[(2-hydroxyphenyl)methyl]-6-methoxyphenyl]-3-phenylpropan-1-one

Uvaretin生物活性

• 描述: uvaretin和isouvaretin的混合物(HY-N10130)对枯草杆菌(EC50 8.7μM)和表皮葡萄球菌(IC50 7.9μM)具有显著的抗菌活性。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Maeda G, et al. Oxygenated Cyclohexene Derivatives from the Stem and Root Barks of Uvaria pandensis. J Nat Prod. 2021 Nov 21.

Uvaretin物理化学性质

• 密度: 1.274g/cm3
• 沸点: 620.2ºC at 760 mmHg
• 分子式: C₂₃H₂₂O₅
• 分子量: 378.42
• 闪点: 217.8ºC
• 精确质量: 378.14700
• PSA: 86.99000
• LogP: 4.21830
• InChIKey: LQHGGFQNRNEFIG-UHFFFAOYSA-N
• SMILES: COc1cc(O)c(Cc2ccccc2O)c(O)c1C(=O)CCc1ccccc1
• 折射率: 1.64

Uvaretin靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse P388 cells relative to control 来源：ChEMBL 靶标：P388 External Id：CHEMBL966629

实验名称：Antimalarial activity against Plasmodium falciparum K1 by [3H]hypoxanthine uptake 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL1004272

实验名称：Antiproliferative activity against human A-431 cells overexpressing EGFR assessed as ... 来源：ChEMBL 靶标：A-431 External Id：CHEMBL5133515

实验名称：Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation me... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL5237630

实验名称：Antibacterial activity against Escherichia coli at 5 mM incubated for 18 hrs by Alama... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4604518

实验名称：Antibacterial activity against Pseudomonas putida NBRC/ATCC 100650 assessed as reduct... 来源：ChEMBL 靶标：Pseudomonas putida External Id：CHEMBL5237629

实验名称：Antibacterial activity against Paraburkholderia caledonica NBRC/ATCC 102488 assessed ... 来源：ChEMBL 靶标：Paraburkholderia caledonica External Id：CHEMBL5237631

实验名称：Antibacterial activity against Escherichia coli MG1655 assessed as reduction in bacte... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL5237626

实验名称：Cytotoxicity against human A549 cells assessed as reduction in cell viability incubat... 来源：ChEMBL 靶标：A549 External Id：CHEMBL4334672

实验名称：Antibacterial activity against Staphylococcus epidermidis ATCC 35984 assessed as redu... 来源：ChEMBL 靶标：Staphylococcus epidermidis External Id：CHEMBL5237625

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Uvaretin英文别名

• Uvaretin