整合素拮抗剂27

• 常用名: 整合素拮抗剂27
• 英文名: Integrin Antagonists 27
• CAS号: 593274-97-6
• 分子量: 444.44
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₀N₄O₅
• 熔点: N/A
• 闪点: N/A

整合素拮抗剂27用途

Integrin Antagonists 27是一种小分子整合蛋白αvβ3拮抗剂, 亲和力为18 nM, 用作抗癌剂。

整合素拮抗剂27名称

• 中文名: 整合素拮抗剂27
• 英文名: Integrin Antagonists 27

整合素拮抗剂27生物活性

• 描述: Integrin Antagonists 27是一种小分子整合蛋白αvβ3拮抗剂, 亲和力为18 nM, 用作抗癌剂。
• 相关类别:
  信号通路 >> 细胞骨架 >> Integrin
  研究领域 >> 癌症
• 参考文献:

  [1]. Dayam R, et al. Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents. J Med Chem. 2006 Jul 27;49(15):4526-4534.

整合素拮抗剂27物理化学性质

• 分子式: C₂₄H₂₀N₄O₅
• 分子量: 444.44
• InChIKey: BJCKKLXERBMNHP-MOSHPQCFSA-N
• SMILES: Cc1ccc(NC(=O)CN2C(=O)NC(=Cc3cccn3-c3cccc(C(=O)O)c3)C2=O)cc1
• 储存条件: 2-8℃

整合素拮抗剂27靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Primary qHTS for Identification of Calcium Integrin Binding Protein 1 (CIB1) Competit... 来源：NCGC External Id：CIB1-p1-p2

实验名称：uHTS identification of small molecule modulators of NR3A 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：SBCCG-A1015-NR3A-Primary-Assay

实验名称：MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint... 来源：Broad Institute 靶标：N/A External Id：2084-01_Activator_SinglePoint_HTS_Activity

共103条，当前第1页，共11页

1

2

3

4

5