光甘草酮

• 常用名: 光甘草酮
• 英文名: Glabrone
• CAS号: 60008-02-8
• 分子量: 336.33800
• 密度: 1.368g/cm3
• 沸点: 554.1ºC at 760 mmHg
• 分子式: C₂₀H₁₆O₅
• 熔点: N/A
• 闪点: 202.6ºC

光甘草酮用途

Glabrone 是从甘草根中分离的一种异黄酮。Glabrone 具有抗流感活性和显著的 PPAR-γ 配体结合活性。

光甘草酮名称

• 中文名: 光果甘草酮
• 英文名: 7-hydroxy-3-(5-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one

光甘草酮生物活性

• 描述: Glabrone 是从甘草根中分离的一种异黄酮。Glabrone 具有抗流感活性和显著的 PPAR-γ 配体结合活性。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> PPAR
  研究领域 >> 代谢疾病
• 靶点实验:

  PPAR-γ

• 参考文献:

  [1]. Grienke U, et al. Computer-guided approach to access the anti-influenza activity of licorice constituents. J Nat Prod. 2014 Mar 28;77(3):563-70.

  [2]. Kuroda M, et al. Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. Bioorg Med Chem. 2010 Jan 15;18(2):962-70.

光甘草酮物理化学性质

• 密度: 1.368g/cm3
• 沸点: 554.1ºC at 760 mmHg
• 分子式: C₂₀H₁₆O₅
• 分子量: 336.33800
• 闪点: 202.6ºC
• 精确质量: 336.10000
• PSA: 79.90000
• LogP: 4.05540
• InChIKey: COLMVFWKLOZOOP-UHFFFAOYSA-N
• SMILES: CC1(C)C=Cc2c(ccc(-c3coc4cc(O)ccc4c3=O)c2O)O1
• 折射率: 1.659
• 储存条件: 2-8°C，干燥，密封

光甘草酮安全信息

• 危害码 (欧洲): Xi
• 海关编码: 2914400090

光甘草酮海关

• 海关编码: 2914400090
• 中文概述: 2914400090 其他酮醇及酮醛。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 丙酮报明包装
• Summary: 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

光甘草酮靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemilumi... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL3131472

实验名称：Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by c... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL3131473

实验名称：Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemilu... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL3131474

实验名称：Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based as... 来源：ChEMBL 靶标：Neuraminidase External Id：CHEMBL3131475

实验名称：Antiproliferative activity against human SW480 cells at 10 uM after 24 hrs by MTS ass... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL4053426

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Primary cell-based high-throughput screening for identification of compounds that all... 来源：Johns Hopkins Ion Channel Center 靶标：MAS-related GPR member X1 [Homo sapiens] External Id：JHICC_MrgX1_AlloAgonist_Primary

实验名称：Primary cell-based high-throughput screening for identification of compounds that ant... 来源：Johns Hopkins Ion Channel Center 靶标：MAS-related GPR member X1 [Homo sapiens] External Id：JHICC_MrgX1_Antagonist_Primary

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

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光甘草酮英文别名

• 7,5'-dihydroxy-2',2'-dimethyl-2'H-[3,6']bichromenyl-4-one
• Morusin hydroperoxide
• 4H-1-Benzopyran-4-one,7-hydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)
• Glabrone
• HMS2268B14