人参皂苷F2

• 常用名: 人参皂苷F2
• 英文名: Ginsenoside F2
• CAS号: 62025-49-4
• 分子量: 785.013
• 密度: 1.3±0.1 g/cm3
• 沸点: 871.5±65.0 °C at 760 mmHg
• 分子式: C₄₂H₇₂O₁₃
• 熔点: 185 °C
• 闪点: 480.9±34.3 °C

人参皂苷F2用途

Ginsenoside F2 是Ginsenoside Rb1 的代谢物,可诱导乳腺癌干细胞的凋亡和保护性自噬。

人参皂苷F2名称

• 中文名: 人参皂苷F2
• 英文名: ginsenoside F2
• 中文别名: 人参皂苷F2 | 人参皂苷 F2 | 人参皂苷-F2

人参皂苷F2生物活性

• 描述: Ginsenoside F2 是Ginsenoside Rb1 的代谢物,可诱导乳腺癌干细胞的凋亡和保护性自噬。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 癌症
  信号通路 >> 自噬 >> 自噬
• 参考文献:

  [1]. Mai TT, et al. Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells. Cancer Lett. 2012 Aug 28;321(2):144-53.

人参皂苷F2物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 871.5±65.0 °C at 760 mmHg
• 熔点: 185 °C
• 分子式: C₄₂H₇₂O₁₃
• 分子量: 785.013
• 闪点: 480.9±34.3 °C
• 精确质量: 784.497314
• PSA: 218.99000
• LogP: 3.53
• InChIKey: SWIROVJVGRGSPO-JBVRGBGGSA-N
• SMILES: CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C1CCC2(C)C1C(O)CC1C3(C)CCC(OC4OC(CO)C(O)C(O)C4O)C(C)(C)C3CCC12C
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.594
• 储存条件: 0-10°C;避免加热

人参皂苷F2靶点实验

查看更多实验

实验名称：Cytotoxicity against human HL60 cells at 25 uM after 48 hrs by WST8 assay 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1111933

实验名称：Inhibition of cell proliferation of rat C6 cells assessed as cell viability at 100 uM... 来源：ChEMBL 靶标：C6 External Id：CHEMBL3385797

实验名称：Cytotoxicity against human PC3 cells at 25 uM after 48 hrs by WST8 assay 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL1111931

实验名称：Cytotoxicity against mouse LM1 cells assessed as cell growth inhibition upto 100 uM a... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3532596

实验名称：Cytotoxicity against human A549 cells at 25 uM after 48 hrs by WST8 assay 来源：ChEMBL 靶标：A549 External Id：CHEMBL1111929

实验名称：Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel... 来源：ChEMBL 靶标：DNA topoisomerase 2-alpha External Id：CHEMBL1111927

实验名称：Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel... 来源：ChEMBL 靶标：DNA topoisomerase 1 External Id：CHEMBL1111926

实验名称：Cytotoxicity against human PANC1 cells at 25 uM after 48 hrs by WST8 assay 来源：ChEMBL 靶标：PANC-1 External Id：CHEMBL1111935

实验名称：Inhibition of cell proliferation of human U251 cells assessed as cell viability at 10... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3385796

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人参皂苷F2英文别名

• β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl
• 20(S)-Ginsenoside-F2
• (3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl β-D-glucopyranoside
• GINSENOSIDE F2
• GinsenosideF2