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2'-Deoxy-2'-fluoro-L-uridine

更新时间:2024-01-07 17:56:17

2'-Deoxy-2'-fluoro-L-uridine结构式
2'-Deoxy-2'-fluoro-L-uridine结构式
品牌特惠专场
常用名 2'-Deoxy-2'-fluoro-L-uridine 英文名 2'-Deoxy-2'-fluoro-L-uridine
CAS号 622785-69-7 分子量 246.19200
密度 N/A 沸点 N/A
分子式 C9H11FN2O5 熔点 N/A
MSDS N/A 闪点 N/A

 2'-Deoxy-2'-fluoro-L-uridine用途


2'-脱氧-2'-氟-1-尿苷是一种l-核苷化合物。2'-脱氧-2'-氟-1-尿苷是一种有效的、选择性的病毒RNA聚合酶抑制剂,从而抑制RNA病毒复制[1]。

 2'-Deoxy-2'-fluoro-L-uridine名称

英文名 1-(2-Deoxy-2-fluoro-β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione
英文别名 更多

 2'-Deoxy-2'-fluoro-L-uridine生物活性

描述 2'-脱氧-2'-氟-1-尿苷是一种l-核苷化合物。2'-脱氧-2'-氟-1-尿苷是一种有效的、选择性的病毒RNA聚合酶抑制剂,从而抑制RNA病毒复制[1]。
相关类别

 2'-Deoxy-2'-fluoro-L-uridine物理化学性质

分子式 C9H11FN2O5
分子量 246.19200
精确质量 246.06500
PSA 104.81000

 2'-Deoxy-2'-fluoro-L-uridine合成线路

~%

2'-Deoxy-2'-fluoro-L-uridine结构式

2'-Deoxy-2'-flu...

622785-69-7

文献:Choi, Yongseok; Li, Ling; Grill, Sue; Gullen, Elizabeth; Lee, Chang Soo; Gumina, Giuseppe; Tsujii, Eisaku; Cheng, Yung-Chi; Chu, Chung K. Journal of Medicinal Chemistry, 2000 , vol. 43, # 13 p. 2538 - 2546

~%

2'-Deoxy-2'-fluoro-L-uridine结构式

2'-Deoxy-2'-flu...

622785-69-7

文献:NOXXON Pharma AG Patent: US2006/183700 A1, 2006 ; Location in patent: Page/Page column 25; Figure 15 ;

~82%

2'-Deoxy-2'-fluoro-L-uridine结构式

2'-Deoxy-2'-flu...

622785-69-7

文献:Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652

~%

2'-Deoxy-2'-fluoro-L-uridine结构式

2'-Deoxy-2'-flu...

622785-69-7

文献:Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Hassan, Abdalla E. A.; Tharnish, Phillip M.; McBrayer, Tamara R.; Lostia, Stefania; Stuyver, Lieven J.; Watanabe, Kyoichi A.; Chu, Chung K.; Schinazi, Raymond F.; Otto, Michael J. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 875 - 879

~%

2'-Deoxy-2'-fluoro-L-uridine结构式

2'-Deoxy-2'-flu...

622785-69-7

文献:Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652

~%

2'-Deoxy-2'-fluoro-L-uridine结构式

2'-Deoxy-2'-flu...

622785-69-7

文献:Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652

 2'-Deoxy-2'-fluoro-L-uridine英文别名

(S)-2-chloro-butyric acid dimethylamide
L-2-Chlor-N,N-dimethyl-butyramid
L-2'-deoxy-2'-fluorouridine
(S)-2-Chlor-buttersaeure-dimethylamid
2-Chloro-N,N-dimethylbutyramide
Butanamide,2-chloro-N,N-dimethyl
2'-fluoro-L-uridine