2'-Deoxy-2'-fluoro-L-uridine

Modify Date: 2024-01-07 17:56:17

2'-Deoxy-2'-fluoro-L-uridine Structure
2'-Deoxy-2'-fluoro-L-uridine structure
Common Name 2'-Deoxy-2'-fluoro-L-uridine
CAS Number 622785-69-7 Molecular Weight 246.19200
Density N/A Boiling Point N/A
Molecular Formula C9H11FN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-Deoxy-2'-fluoro-L-uridine


2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication[1].

 Names

Name 1-(2-Deoxy-2-fluoro-β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione
Synonym More Synonyms

 2'-Deoxy-2'-fluoro-L-uridine Biological Activity

Description 2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication[1].
Related Catalog

 Chemical & Physical Properties

Molecular Formula C9H11FN2O5
Molecular Weight 246.19200
Exact Mass 246.06500
PSA 104.81000

 Synthetic Route

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2'-Deoxy-2'-fluoro-L-uridine Structure

2'-Deoxy-2'-flu...

CAS#:622785-69-7

Literature: Choi, Yongseok; Li, Ling; Grill, Sue; Gullen, Elizabeth; Lee, Chang Soo; Gumina, Giuseppe; Tsujii, Eisaku; Cheng, Yung-Chi; Chu, Chung K. Journal of Medicinal Chemistry, 2000 , vol. 43, # 13 p. 2538 - 2546

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2'-Deoxy-2'-fluoro-L-uridine Structure

2'-Deoxy-2'-flu...

CAS#:622785-69-7

Literature: NOXXON Pharma AG Patent: US2006/183700 A1, 2006 ; Location in patent: Page/Page column 25; Figure 15 ;

~82%

2'-Deoxy-2'-fluoro-L-uridine Structure

2'-Deoxy-2'-flu...

CAS#:622785-69-7

Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652

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2'-Deoxy-2'-fluoro-L-uridine Structure

2'-Deoxy-2'-flu...

CAS#:622785-69-7

Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Hassan, Abdalla E. A.; Tharnish, Phillip M.; McBrayer, Tamara R.; Lostia, Stefania; Stuyver, Lieven J.; Watanabe, Kyoichi A.; Chu, Chung K.; Schinazi, Raymond F.; Otto, Michael J. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 875 - 879

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2'-Deoxy-2'-fluoro-L-uridine Structure

2'-Deoxy-2'-flu...

CAS#:622785-69-7

Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652

~%

2'-Deoxy-2'-fluoro-L-uridine Structure

2'-Deoxy-2'-flu...

CAS#:622785-69-7

Literature: Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652

 Synonyms

(S)-2-chloro-butyric acid dimethylamide
L-2-Chlor-N,N-dimethyl-butyramid
L-2'-deoxy-2'-fluorouridine
(S)-2-Chlor-buttersaeure-dimethylamid
2-Chloro-N,N-dimethylbutyramide
Butanamide,2-chloro-N,N-dimethyl
2'-fluoro-L-uridine
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