21-脱氧皮质醇

• 常用名: 21-脱氧皮质醇
• 英文名: 11beta,17alpha-dihydroxy-4-pregnene-3,20-dione
• CAS号: 641-77-0
• 分子量: 346.46100
• 密度: 1.21g/cm3
• 沸点: 523.9ºC at 760 mmHg
• 分子式: C₂₁H₃₀O₄
• 熔点: N/A
• 闪点: 284.7ºC
• 符号: GHS02, GHS06, GHS08
• 信号词: Danger

21-脱氧皮质醇用途

21脱氧皮质醇是一种内源性代谢产物。21脱氧皮质素是先天性肾上腺增生的标志[1]。

21-脱氧皮质醇名称

• 中文名: 11beta,17alpha-二羟基-4-孕烯-3,20-二酮
• 英文名: 11beta,17alpha-dihydroxy-4-pregnene-3,20-dione

21-脱氧皮质醇生物活性

• 描述: 21脱氧皮质醇是一种内源性代谢产物。21脱氧皮质素是先天性肾上腺增生的标志[1]。
• 相关类别:
  研究领域 >> 内分泌
• 靶点实验:

  Human Endogenous Metabolite

• 参考文献:

  [1]. Franks RC. Plasma 17-hydroxyprogesterone, 21-deoxycortisol and cortisol in congenital adrenal hyperplasia. J Clin Endocrinol Metab. 1974;39(6):1099-1102.

21-脱氧皮质醇物理化学性质

• 密度: 1.21g/cm3
• 沸点: 523.9ºC at 760 mmHg
• 分子式: C₂₁H₃₀O₄
• 分子量: 346.46100
• 闪点: 284.7ºC
• 精确质量: 346.21400
• PSA: 74.60000
• LogP: 2.80920
• InChIKey: LCZBQMKVFQNSJR-UJPCIWJBSA-N
• SMILES: CC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC21C
• 折射率: 1.576
• 储存条件: ?20°C

21-脱氧皮质醇安全信息

• 符号: GHS02, GHS06, GHS08
• 信号词: Danger
• 危害声明: H225-H301 + H311 + H331-H370
• 警示性声明: P210-P260-P280-P301 + P310-P311
• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危害码 (欧洲): F,T
• 风险声明 (欧洲): 11-23/24/25-39/23/24/25
• 安全声明 (欧洲): 7-16-36/37-45
• 危险品运输编码: UN1230 - class 3 - PG 2 - Methanol, solution

21-脱氧皮质醇靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Validation... 来源：NMMLSC 靶标：ATP-binding cassette sub-family B member 6, mitochondrial [Homo sapiens] External Id：UNMCMD_ABCB6_1o_ValidationSet

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

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21-脱氧皮质醇英文别名

• 21-deoxycortisol
• 21-Deoxyhydrocortisone
• 21-Dehydrohydrocortisone
• 21-DESOXYCORTISOL
• 21 DEOXYCORTISOL 21-DESOXYCORTISOL
• 4-pregnene-11-B-17-A-diol-3-20-dione
• 4-Pregnen-11,17a-diol-3,20-dione-d8
• EINECS 211-375-7