Altholactone

• 常用名: Altholactone
• 英文名: Altholactone
• CAS号: 65408-91-5
• 分子量: 232.23
• 密度: 1.3±0.1 g/cm3
• 沸点: 490.4±45.0 °C at 760 mmHg
• 分子式: C₁₃H₁₂O₄
• 熔点: N/A
• 闪点: 196.1±22.2 °C
• 符号: GHS06
• 信号词: Danger

Altholactone用途

Goniothalenol 是一种从 Goniothalamus griffithii 中分离得到的苯乙烯内酯。Goniothalenol 对 A2780、HCT-8、KB 和 MCF-7 细胞系具有细胞毒活性。

Altholactone名称

• 英文名: (2R,3R,3aS,7aS)-3-hydroxy-2-phenyl-2,3,3a,7a-tetrahydrofuro[3,2-b]pyran-5-one

Altholactone生物活性

• 描述: Goniothalenol 是一种从 Goniothalamus griffithii 中分离得到的苯乙烯内酯。Goniothalenol 对 A2780、HCT-8、KB 和 MCF-7 细胞系具有细胞毒活性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Zhang, Y. J., et al. Styryllactones from the Rhizomes ofGoniothalamus griffithii. Journal of Asian Natural Products Research, 1(3), 189–197.

Altholactone物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 490.4±45.0 °C at 760 mmHg
• 分子式: C₁₃H₁₂O₄
• 分子量: 232.23
• 闪点: 196.1±22.2 °C
• 精确质量: 232.073563
• PSA: 55.76000
• LogP: 1.00
• InChIKey: ZKIRVBNLJKGIEM-WKSBVSIWSA-N
• SMILES: O=C1C=CC2OC(c3ccccc3)C(O)C2O1
• 外观性状: 油状物体
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.598
• 储存条件: ?20°C

Altholactone安全信息

• 符号: GHS06
• 信号词: Danger
• 危害声明: H301
• 警示性声明: P301 + P310
• 危害码 (欧洲): T
• 风险声明 (欧洲): 25
• 安全声明 (欧洲): 45
• 危险品运输编码: UN 2811 6.1 / PGIII

Altholactone靶点实验

查看更多实验

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction of LPS-induce... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL2401331

实验名称：Cytotoxicity against human LNCAP cells up to 100 uM after 20 hrs by MTT assay 来源：ChEMBL 靶标：LNCaP External Id：CHEMBL2401319

实验名称：Cytotoxicity against human PC3 cells up to 100 uM after 20 hrs by MTT assay 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL2401318

实验名称：Inhibition of noradrenaline-induced contractile response in rat aorta at 100 uM in pr... 来源：ChEMBL 靶标：Aorta External Id：CHEMBL960222

实验名称：Antimycobacterial activity against Mycobacterium tuberculosis H37Ra 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL2209268

实验名称：Cytotoxicity against mouse L1210 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：L1210 External Id：CHEMBL978543

实验名称：Cytotoxicity against human MCF10A cells up to 100 uM after 20 hrs by MTT assay 来源：ChEMBL 靶标：MCF-10A External Id：CHEMBL2401322

实验名称：Cytotoxicity against human MDA-MB-231 cells up to 100 uM after 20 hrs by MTT assay 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL2401321

实验名称：Cytotoxicity against human MCF7 cells up to 100 uM after 20 hrs by MTT assay 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL2401320

实验名称：Cell cycle arrest in mouse L1210 cells by accumulation at G2M phase after 21 hrs rela... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL978544

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Altholactone英文别名

• 2-phenyl-3-hydroxy-6,7-dihydro-furano-pyrone
• (2R,3R,3aS,7aS)-3-Hydroxy-2-phenyl-2,3,3a,7a-tetrahydro-5H-furo[3,2-b]pyran-5-one
• goniothalenol