算盘子酮

• 常用名: 算盘子酮
• 英文名: Glochidone
• CAS号: 6610-55-5
• 分子量: 422.69
• 密度: 1.0±0.1 g/cm3
• 沸点: 489.8±25.0 °C at 760 mmHg
• 分子式: C₃₀H₄₆O
• 熔点: N/A
• 闪点: 258.1±14.0 °C

算盘子酮用途

Glochidone是一种抗癌药物,其抗HOP-62和EPLC-272H细胞的IC50分别为5.52μM和7.84μM[1]。

算盘子酮名称

• 中文名: 算盘子酮
• 英文名: Lupa-1,20(29)-dien-3-one

算盘子酮生物活性

• 描述: Glochidone是一种抗癌药物,其抗HOP-62和EPLC-272H细胞的IC50分别为5.52μM和7.84μM[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Chen H, et al. Glochidiol, a natural triterpenoid, exerts its anti-cancer effects by targeting the colchicine binding site of tubulin. Invest New Drugs. 2021 Apr;39(2):578-586.

算盘子酮物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 489.8±25.0 °C at 760 mmHg
• 分子式: C₃₀H₄₆O
• 分子量: 422.69
• 闪点: 258.1±14.0 °C
• 精确质量: 422.354858
• PSA: 17.07000
• LogP: 10.09
• InChIKey: FWBYBHVDDGVPDF-BHMAJAPKSA-N
• SMILES: C=C(C)C1CCC2(C)CCC3(C)C(CCC4C5(C)C=CC(=O)C(C)(C)C5CCC43C)C12
• 外观性状: 粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.517
• 储存条件: 2-8℃，干燥，密闭

算盘子酮安全信息

• 危害码 (欧洲): Xi

算盘子酮靶点实验

查看更多实验

实验名称：Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：Vero External Id：CHEMBL1003500

实验名称：Cytotoxicity against human HeLa cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL1003498

实验名称：Cytotoxicity against human Hep2 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HEp-2 External Id：CHEMBL1003499

实验名称：Antifungal activity against Candida albicans UBC1 up to 40 ug/mL by broth microdiluti... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL1003494

实验名称：Antiviral activity against HIV1 NL4.3-Ren infected in human MT2 cells assessed as inh... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL3584165

实验名称：Antibacterial activity against Enterococcus faecalis CECT 795 up to 40 ug/mL by broth... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL1002770

实验名称：Antibacterial activity against Bacillus subtilis CECT 39 up to 40 ug/mL by broth micr... 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL1002771

实验名称：Antibacterial activity against Staphylococcus epidermidis CECT 232 up to 40 ug/mL by ... 来源：ChEMBL 靶标：Staphylococcus epidermidis External Id：CHEMBL1002768

实验名称：Antibacterial activity against Staphylococcus saprophyticus CECT 235 up to 40 ug/mL b... 来源：ChEMBL 靶标：Staphylococcus saprophyticus External Id：CHEMBL1002769

实验名称：Antibacterial activity against Staphylococcus aureus ATCC 6538 up to 40 ug/mL by brot... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1002767

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算盘子酮英文别名

• Betuline
• TROCHOL
• betula camphor
• BETULOL
• BETULINOL
• betulinic alcohol
• Lupa-1,20(29)-dien-3-one
• Glochidone