羽扇烯酮

• 常用名: 羽扇烯酮
• 英文名: Lupenone
• CAS号: 1617-70-5
• 分子量: 424.702
• 密度: 1.0±0.1 g/cm3
• 沸点: 487.9±12.0 °C at 760 mmHg
• 分子式: C₃₀H₄₈O
• 熔点: 165-167ºC
• 闪点: 278.4±5.7 °C

羽扇烯酮用途

Lupenone 是从 Rhizoma Musae 中分离出的 lupine 型三萜类化合物。Lupenone 具有各种药理活性,包括抗炎,抗病毒,抗糖尿病,抗癌,改善南美锥虫病而无主要毒性。

羽扇烯酮名称

• 中文名: 羽扇烯酮
• 英文名: lupenone

羽扇烯酮生物活性

• 描述: Lupenone 是从 Rhizoma Musae 中分离出的 lupine 型三萜类化合物。Lupenone 具有各种药理活性,包括抗炎,抗病毒,抗糖尿病,抗癌,改善南美锥虫病而无主要毒性。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Xu F, et al. Beneficial health effects of lupenone triterpene: A review. Biomed Pharmacother. 2018 Jul;103:198-203.

  [2]. Xu F, et al. Lupenone is a good anti-inflammatory compound based on the network pharmacology. Mol Divers. 2019 Feb 22.

羽扇烯酮物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 487.9±12.0 °C at 760 mmHg
• 熔点: 165-167ºC
• 分子式: C₃₀H₄₈O
• 分子量: 424.702
• 闪点: 278.4±5.7 °C
• 精确质量: 424.370514
• PSA: 17.07000
• LogP: 10.39
• InChIKey: GRBHNQFQFHLCHO-BHMAJAPKSA-N
• SMILES: C=C(C)C1CCC2(C)CCC3(C)C(CCC4C5(C)CCC(=O)C(C)(C)C5CCC43C)C12
• 外观性状: 粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.510
• 储存条件: 2-8℃，干燥，密闭，避光

羽扇烯酮安全信息

• 危害码 (欧洲): Xi
• 海关编码: 29142990

羽扇烯酮靶点实验

查看更多实验

实验名称：Antifungal activity against Phytophthora cactorum at 10 mg/L in liquid culture medium 来源：ChEMBL 靶标：Phytophthora cactorum External Id：CHEMBL1028473

实验名称：Antiproliferative activity in human HeLa cells by sulforhodamine B assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4135984

实验名称：Antiproliferative activity in human SiHa cells by sulforhodamine B assay 来源：ChEMBL 靶标：SiHa External Id：CHEMBL4135985

实验名称：Antiviral activity against HIV1 NL4.3-Ren infected in human MT2 cells assessed as inh... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL3584165

实验名称：Cytotoxic activity in human HeLa cells by sulforhodamine B assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4135961

实验名称：Cytotoxic activity in African green monkey Vero cells by sulforhodamine B assay 来源：ChEMBL 靶标：Vero External Id：CHEMBL4135968

实验名称：Inhibition of R5-tropic HIV1 envelope glycoprotein-mediated cell-cell fusion between ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2044717

实验名称：Cytotoxic activity in HEK293 cells by sulforhodamine B assay 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL4135969

实验名称：Cytotoxic activity in human KB cells by sulforhodamine B assay 来源：ChEMBL 靶标：KB External Id：CHEMBL4135966

实验名称：Cytotoxic activity in human Hep2 cells by sulforhodamine B assay 来源：ChEMBL 靶标：HEp-2 External Id：CHEMBL4135967

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羽扇烯酮英文别名

• Lupenone
• (1R,3aR,4S,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-Isopropenyl-3a,5a,5b,8,8,11a-hexamethyl-eicosahydro-cyclopenta[a]chrysen-9-one
• (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexaméthyl-1-(1-propèn-2-yl)icosahydro-9H-cyclopenta[a]chrysén-9-one
• (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-Isopropenyl-3a,5a,5b,8,8,11a-hexamethylicosahydro-9H-cyclopenta[a]chrysen-9-one
• Lup-2-en-1-one
• (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-Isopropenyl-3a,5a,5b,8,8,11a-hexamethylicosahydro-9H-cyclopenta[a]chrysen-9-on
• Lup-20(29)-en-3-one
• Lup-20(30)-en-3-one
• 18-lupen-3-one