N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺

• 常用名: N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺
• 英文名: N-Feruloyloctopamine
• CAS号: 66648-44-0
• 分子量: 329.347
• 密度: 1.3±0.1 g/cm3
• 沸点: 652.5±55.0 °C at 760 mmHg
• 分子式: C₁₈H₁₉NO₅
• 熔点: N/A
• 闪点: 348.4±31.5 °C

N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺用途

N-Feruloyloctopamine,从 Garlic 皮中分离出来的,是一种抗氧化剂成分。N-Feruloyloctopamine 显着降低 Akt 和 p38MAPK 磷酸化水平。

N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺名称

• 中文名: N-阿魏酰章鱼胺
• 英文名: Chloro(dodecyl)dimethylsilane
• 中文别名: N-阿魏酰真蛸胺

N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺生物活性

• 描述: N-Feruloyloctopamine,从 Garlic 皮中分离出来的,是一种抗氧化剂成分。N-Feruloyloctopamine 显着降低 Akt 和 p38MAPK 磷酸化水平。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> PI3K/Akt/mTOR 信号通路 >> AKT
  信号通路 >> MAPK/ERK信号通路 >> p38 MAPK
• 靶点实验:

  Akt

  p38 MAPK

• 参考文献:

  [1]. Bai ZT, et al. Inhibition of invasion by N-trans-feruloyloctopamine via AKT, p38MAPK and EMT related signals in hepatocellular carcinoma cells. Bioorg Med Chem Lett. 2017 Feb 15;27(4):989-993.

N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 652.5±55.0 °C at 760 mmHg
• 分子式: C₁₈H₁₉NO₅
• 分子量: 329.347
• 闪点: 348.4±31.5 °C
• 精确质量: 329.126312
• PSA: 99.02000
• LogP: 1.03
• InChIKey: VJSCHQMOTSXAKB-YCRREMRBSA-N
• SMILES: COc1cc(C=CC(=O)NCC(O)c2ccc(O)cc2)ccc1O
• 外观性状: 粉末
• 蒸汽压: 0.0±2.1 mmHg at 25°C
• 折射率: 1.656
• 储存条件: 2-8℃，干燥，密闭

N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺安全信息

• 危害码 (欧洲): Xi

N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺靶点实验

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实验名称：Neuroprotective activity against glutamate-induced excitotoxicity in rat PC12 cells a... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL5389940

实验名称：Neuroprotective activity against glutamate-induced excitotoxicity in rat PC12 cells a... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL5389939

实验名称：Neuroprotective activity against glutamate-induced excitotoxicity in rat PC12 cells a... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL5389938

实验名称：Positive allosteric modulation of GluN1/N2B (unknown origin) transfected in HEK293 ce... 来源：ChEMBL 靶标：Glutamate receptor ionotropic, NMDA 2B External Id：CHEMBL5389935

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实验名称：Reduction in p38 phosphorylation in human HCCLM3 cells at 2 mM after 48 hrs by wester... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 11 External Id：CHEMBL3995714

实验名称：Reduction in p38 phosphorylation in human HuH7 cells at 2 mM after 48 hrs by western ... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 11 External Id：CHEMBL3995713

实验名称：Downregulation of slug in human HCCLM3 cells at 2 mM after 48 hrs by western blot ana... 来源：ChEMBL 靶标：HCCLM3 External Id：CHEMBL3995716

实验名称：Upregulation of E-cadherin in human HCCLM3 cells after 48 hrs by western blot analysi... 来源：ChEMBL 靶标：HCCLM3 External Id：CHEMBL3995715

实验名称：Effect on ERK1/2 phosphorylation in human HCCLM3 cells at 2 mM after 48 hrs by wester... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 3 External Id：CHEMBL3995710

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N-阿魏酰真蛸胺; N- 阿魏酰章鱼胺英文别名

• N-trans-feruloyl 3-O-methyldopamine
• (2E)-N-[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)acrylamide
• N-trans-feruloy-3-O-methyldopamine
• N-trans-feruloyl octopamine
• N-trans-Feruloyloctopamin
• trans-N-feruloyloctopamine
• trans-N-feruloyl-3-O-methyldopamine
• N-trans-Feruloylmethoxytyramine