10-羟基喜树碱

• 常用名: 10-羟基喜树碱
• 英文名: 9-Hydroxycamptothecin
• CAS号: 67656-30-8
• 分子量: 364.351
• 密度: 1.6±0.1 g/cm3
• 沸点: 820.7±65.0 °C at 760 mmHg
• 分子式: C₂₀H₁₆N₂O₅
• 熔点: N/A
• 闪点: 450.1±34.3 °C

10-羟基喜树碱用途

9-Hydroxycamptothecin (9-Hydroxycamptothecine) 是一种具有抗癌活性的喜树碱衍生物,详细信息请参考专利文献 WO1999001456A1 中的化合物 23c。

10-羟基喜树碱名称

• 中文名: 10-羟基喜树碱
• 英文名: 3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10-dione
• 中文别名: 10-羟基喜树碱 | 4-乙基-4,10-二羟基-1H-吡喃[3',4':6,7]吲哚[1,2-b]喹啉-3,14(4H,12H)-二酮

10-羟基喜树碱生物活性

• 描述: 9-Hydroxycamptothecin (9-Hydroxycamptothecine) 是一种具有抗癌活性的喜树碱衍生物,详细信息请参考专利文献 WO1999001456A1 中的化合物 23c。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Dennis P. Curran, et al. Synthesis of and intermediates for camptothecins. WO1999001456A1.

10-羟基喜树碱物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 820.7±65.0 °C at 760 mmHg
• 分子式: C₂₀H₁₆N₂O₅
• 分子量: 364.351
• 闪点: 450.1±34.3 °C
• 精确质量: 364.105927
• PSA: 101.65000
• LogP: 1.32
• InChIKey: LCZZWLIDINBPRC-FQEVSTJZSA-N
• SMILES: CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(O)cccc3nc2-1
• 外观性状: 固体
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.777
• 储存条件: 2-8°C， 干燥

10-羟基喜树碱安全信息

• 危害码 (欧洲): Xn
• 海关编码: 2934999090

10-羟基喜树碱海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

10-羟基喜树碱靶点实验

查看更多实验

实验名称：High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1303_AS

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1303_FP

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：Confirmation Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) 来源：NCGC 靶标：Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) External Id：TDP1640

实验名称：Inhibition of calf thymus DNA topoisomerase 1-mediated relaxation of supercoiled pBR3... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2427939

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：qHTS for Inhibitors of Polymerase Kappa 来源：NCGC 靶标：DNA polymerase kappa [Homo sapiens] External Id：PolK100

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H... 来源：Southern Research Institute 靶标：CFTR External Id：CF Folding

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10-羟基喜树碱英文别名

• 10-Hydroxycamptothecin
• hydroxycamtothecine
• Camptothecin, 10-hydroxy
• 9-hydroxy-20(S)-camptothecin
• 10-hydroxy-Camptothecin
• 9-hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[g] chromene-5,10-dione
• (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10