山小橘碱

• 常用名: 山小橘碱
• 英文名: Arborine
• CAS号: 6873-15-0
• 分子量: 250.295
• 密度: 1.2±0.1 g/cm3
• 沸点: 421.0±38.0 °C at 760 mmHg
• 分子式: C₁₆H₁₄N₂O
• 熔点: N/A
• 闪点: 208.4±26.8 °C

山小橘碱用途

Arborine 可从 Glycosmis arborea 中分离。Arborine 抑制乙酰胆碱的外周作用并诱导血压下降。

山小橘碱名称

• 中文名: 山柑子碱
• 英文名: 2-benzyl-1-methylquinazolin-4-one

山小橘碱生物活性

• 描述: Arborine 可从 Glycosmis arborea 中分离。Arborine 抑制乙酰胆碱的外周作用并诱导血压下降。
• 相关类别:
  信号通路 >> 神经信号通路 >> mAChR
  研究领域 >> 心血管疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR
• 参考文献:

  [1]. Michael JP. Quinoline, quinazoline and acridone alkaloids. Nat Prod Rep. 2003 Oct;20(5):476-93.

山小橘碱物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 421.0±38.0 °C at 760 mmHg
• 分子式: C₁₆H₁₄N₂O
• 分子量: 250.295
• 闪点: 208.4±26.8 °C
• 精确质量: 250.110611
• PSA: 34.89000
• LogP: 2.25
• InChIKey: XVPZRKIQCKKYNE-UHFFFAOYSA-N
• SMILES: Cn1c(Cc2ccccc2)nc(=O)c2ccccc21
• 外观性状: 黄色粉末
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.622
• 储存条件: 室温

山小橘碱靶点实验

查看更多实验

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Bas... 来源：Broad Institute 靶标：N/A External Id：2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：abhydrolase domain-containing protein 4 isoform 1 [Mus musculus] External Id：ABHD4_INH_FP_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation M... 来源：Broad Institute 靶标：N/A External Id：2146-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Cholera Quorum: HTS for inducers of light production in the absence ofautoinducers us... 来源：Broad Institute 靶标：N/A External Id：2132-01_Agonist_SinglePoint_HTS_Activity

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

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山小橘碱英文别名

• Glycosine
• 2-benzyl-1-methyl-1H-quinazolin-4-one
• 2-Benzyl-1-methyl-4(1H)-quinazolinone
• 1-Methyl-2-benzyl-chinazol-4-on = Arborin
• Glycosin
• 1-Methyl-2-benzyl-4(1H)-chinazolinon (Arborin)
• Arborin
• 2-BENZYL-1-METHYL-QUINAZOLIN-4-ONE
• 2-Benzyl-1-methylquinazolin-4(1H)-one
• Arborine
• 1-Methyl-2-benzyl-chinazolon-(4)
• 2-Benzyl-1-methyl-1H-chinazolin-4-on
• 1-Methyl-2-(phenylmethyl)-4(1H)-quinazolinone
• 2-Benzyl-1-methylquinazol-4-one