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佐芬普利钙

更新时间:2025-08-23 12:15:11

佐芬普利钙结构式
佐芬普利钙结构式
品牌特惠专场
常用名 佐芬普利钙 英文名 Zofenopril calcium
CAS号 81938-43-4 分子量 448.58
密度 1.34 g/cm3 沸点 646.3ºC at 760 mmHg
分子式 C22H22Ca0.5NO4S2 熔点 >250ºC
MSDS 中文版 美版 闪点 344.7ºC
符号 GHS09
GHS09
信号词 Warning

 佐芬普利钙用途


Zofenopril Calcium(SQ26991)是抗氧化剂和血管紧张素转化酶(ACE)抑制剂。

 佐芬普利钙名称

中文名 佐芬普利钙
英文名 zofenopril calcium
中文别名 [(4S)-3-(苯甲酰硫基)-2(S)-甲基丙酰-4-(苯硫基)-L-脯氨酸]钙盐
英文别名 更多

 佐芬普利钙物理化学性质

密度 1.34 g/cm3
沸点 646.3ºC at 760 mmHg
熔点 >250ºC
分子式 C22H22Ca0.5NO4S2
分子量 448.58
闪点 344.7ºC
PSA 228.56000
LogP 7.80660
InChIKey NSYUKKYYVFVMST-LETVYOFWSA-L
SMILES CC(CSC(=O)c1ccccc1)C(=O)N1CC(Sc2ccccc2)CC1C(=O)[O-].CC(CSC(=O)c1ccccc1)C(=O)N1CC(Sc2ccccc2)CC1C(=O)[O-].[Ca+2]
外观性状 白色或发白的结晶粉末
储存条件 Refrigerator

 佐芬普利钙MSDS

 佐芬普利钙安全信息

符号 GHS09
GHS09
信号词 Warning
危害声明 H410
警示性声明 P273-P501
危害码 (欧洲) N
风险声明 (欧洲) 50/53
安全声明 (欧洲) 60-61
危险品运输编码 UN 3077 9 / PGIII

 佐芬普利钙合成线路

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佐芬普利钙结构式

佐芬普利钙

81938-43-4

文献:WO2007/3963 A1, ; Page/Page column 9; 11-12 ;

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佐芬普利钙结构式

佐芬普利钙

81938-43-4

文献:US2009/176860 A1, ; Page/Page column 3 ;

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佐芬普利钙结构式

佐芬普利钙

81938-43-4

文献:WO2010/84515 A2, ; Page/Page column 34 ;

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佐芬普利钙结构式

佐芬普利钙

81938-43-4

文献:WO2010/84515 A2, ; Page/Page column 33-34 ;

 佐芬普利钙上下游产品

佐芬普利钙上游产品  3

佐芬普利钙下游产品  0

 佐芬普利钙文献25

更多文献
Zofenopril plus hydrochlorothiazide fixed combination in the treatment of hypertension and associated clinical conditions.

Cardiovasc. Ther. 27(4) , 275-88, (2009)

Zofenopril, is a highly lipophilic ACE inhibitor, characterized by long-lasting tissue penetration and sustained cardiac ACE inhibition, indicated for the treatment of hypertension and myocardial infa...

Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of zofenopril and its active metabolite zofenoprilat in human plasma.

J. Pharm. Biomed. Anal. 55(3) , 527-32, (2011)

A novel, sensitive and rapid liquid chromatographic-electrospray ionization mass spectrometric method was developed and validated for the determination of zofenopril and its active metabolite zofenopr...

Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits.

J. Cardiovasc. Pharmacol. Ther. 15(4) , 384-92, (2010)

Cough is the most common symptom reported by patients in a primary care setting and is one of the most frequent secondary effects recorded during treatment with angiotensin-converting enzyme (ACE) inh...

 佐芬普利钙靶点实验

查看更多实验

实验名称:qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signa...
来源:824
靶标:AR protein [Homo sapiens]
External Id:MDAN535
实验名称:qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
来源:NCGC
靶标:TDP1 protein [Homo sapiens]
External Id:TDP1100
实验名称:qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
来源:NCGC
靶标:TDP1 protein [Homo sapiens]
External Id:TDP1101
实验名称:qHTS assay to identify small molecule antagonists of the androgen receptor (AR) sign...
来源:824
靶标:N/A
External Id:MDAV150
实验名称:qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cel...
来源:824
靶标:RecName: Full=ATPase family AAA domain-containing protein 5; AltName: Full=Chromosome fragility-associated gene 1 protein
External Id:ELG271
实验名称:qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
来源:824
靶标:thyroid hormone receptor beta isoform 2 [Rattus norvegicus]
External Id:TRN186
实验名称:qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
来源:824
靶标:N/A
External Id:TRV455
实验名称:Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screeni...
来源:NCGC
靶标:N/A
External Id:CPF001
实验名称:qHTS for Inhibitors of binding or entry into cells for Marburg Virus
来源:NCGC
靶标:gene 4 small orf - Marburg virus
External Id:VSVM-OFFLINE
实验名称:qHTS for Inhibitors of binding or entry into cells for Lassa Virus
来源:NCGC
靶标:N/A
External Id:VSVL-OFFLINE
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 佐芬普利钙英文别名

Calcium bis[(2S,4S)-1-[(2S)-3-(benzoylsulfanyl)-2-methylpropanoyl]-4-(phenylsulfanyl)-2-pyrrolidinecarboxylate]
ZOFENOPRIL CALCIUM
Calcium bis[(2S,4S)-1-[(2S)-3-(benzoylsulfanyl)-2-methylpropanoyl]-4-(phenylsulfanyl)pyrrolidine-2-carboxylate]
L-Proline, 1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-, calcium salt, (4S)- (2:1)
MFCD08704648
Zofenopril calcium salt
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