11-O-没食子酰岩白菜素

• 常用名: 11-O-没食子酰岩白菜素
• 英文名: 11-O-Galloylbergenin
• CAS号: 82958-44-9
• 分子量: 480.38
• 密度: 1.7±0.1 g/cm3
• 沸点: 887.5±65.0 °C at 760 mmHg
• 分子式: C₂₁H₂₀O₁₃
• 熔点: 269℃
• 闪点: 311.3±27.8 °C

11-O-没食子酰岩白菜素用途

11-O-没食子酸岩白菜素是从菲律宾马洛托斯乙醇提取物中分离得到的一种化合物。11-O-没食子酸岩白菜素具有镇痛和抗炎活性。11-O-没食子酸岩白菜素是一种用于治疗疼痛和炎症的先导化合物[1]。

11-O-没食子酰岩白菜素名称

• 中文名: 11-O-没食子酰岩白菜素
• 英文名: ((2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-9-methoxy-6-oxo-2,3,4,4a,6,10b-hexahydropyrano[3,2-c]isochromen-2-yl)methyl 3,4,5-trihydroxybenzoate

11-O-没食子酰岩白菜素生物活性

• 描述: 11-O-没食子酸岩白菜素是从菲律宾马洛托斯乙醇提取物中分离得到的一种化合物。11-O-没食子酸岩白菜素具有镇痛和抗炎活性。11-O-没食子酸岩白菜素是一种用于治疗疼痛和炎症的先导化合物[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Arfan M, et al. Analgesic and anti-inflammatory activities of 11-O-galloylbergenin. J Ethnopharmacol. 2010;131(2):502-504.

11-O-没食子酰岩白菜素物理化学性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 887.5±65.0 °C at 760 mmHg
• 熔点: 269℃
• 分子式: C₂₁H₂₀O₁₃
• 分子量: 480.38
• 闪点: 311.3±27.8 °C
• 精确质量: 480.090393
• PSA: 212.67000
• LogP: 1.81
• InChIKey: CDRRULDABVKKHU-UHFFFAOYSA-N
• SMILES: COc1c(O)cc2c(c1O)C1OC(COC(=O)c3cc(O)c(O)c(O)c3)C(O)C(O)C1OC2=O
• 外观性状: 粉末
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.705
• 储存条件: 室温

11-O-没食子酰岩白菜素安全信息

• 危害码 (欧洲): Xi

11-O-没食子酰岩白菜素靶点实验

查看更多实验

实验名称：Antiglycation activity assessed as inhibition of advanced glycation end product forma... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1809873

实验名称：Inhibition of NFkappaB signaling pathway in LPS-stimulated mouse RAW264.7 cells by EL... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3825116

实验名称：Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as dow... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3825117

实验名称：Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as dow... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3825112

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3824927

实验名称：Antiglycation activity assessed as inhibition of Schiff-base formation at 200 uM 来源：ChEMBL 靶标：N/A External Id：CHEMBL1809867

实验名称：Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in cel... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3824928

实验名称：Antioxidant activity assessed as ABTS free radical scavenging activity at 200 uM 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1809866

实验名称：Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as dow... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3825118

实验名称：Antiglycation activity in bovine serum albumin assessed as inhibition of fructosamine... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL1809869

共12条，当前第1页，共2页

1

2

11-O-没食子酰岩白菜素英文别名

• [(2R,3S,4S,4aR,10bS)-3,4,8,10-Tetrahydroxy-9-methoxy-6-oxo-2,3,4,4a,6,10b-hexahydropyrano[3,2-c]isochromen-2-yl]methyl 3,4,5-trihydroxybenzoate
• Benzoic acid, 3,4,5-trihydroxy-, [(2R,3S,4S,4aR,10bS)-2,3,4,4a,6,10b-hexahydro-3,4,8,10-tetrahydroxy-9-methoxy-6-oxopyrano[3,2-c][2]benzopyran-2-yl]methyl ester