11-O-Galloylbergenin

Modify Date: 2026-07-08 00:00:43

11-O-Galloylbergenin Structure
11-O-Galloylbergenin structure
Common Name 11-O-Galloylbergenin
CAS Number 82958-44-9 Molecular Weight 480.38
Density 1.7±0.1 g/cm3 Boiling Point 887.5±65.0 °C at 760 mmHg
Molecular Formula C21H20O13 Melting Point 269℃
MSDS N/A Flash Point 311.3±27.8 °C

 Use of 11-O-Galloylbergenin


11-O-Galloylbergenin is a compound isolated from ethanolic extract of Mallotus philippinensis. 11-O-Galloylbergenin has analgesic and anti-inflammatory activities. 11-O-Galloylbergenin is a lead compound for management of pain and inflammation[1].

 Names

Name ((2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-9-methoxy-6-oxo-2,3,4,4a,6,10b-hexahydropyrano[3,2-c]isochromen-2-yl)methyl 3,4,5-trihydroxybenzoate
Synonym More Synonyms

 11-O-Galloylbergenin Biological Activity

Description 11-O-Galloylbergenin is a compound isolated from ethanolic extract of Mallotus philippinensis. 11-O-Galloylbergenin has analgesic and anti-inflammatory activities. 11-O-Galloylbergenin is a lead compound for management of pain and inflammation[1].
Related Catalog
References

[1]. Arfan M, et al. Analgesic and anti-inflammatory activities of 11-O-galloylbergenin. J Ethnopharmacol. 2010;131(2):502-504.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 887.5±65.0 °C at 760 mmHg
Melting Point 269℃
Molecular Formula C21H20O13
Molecular Weight 480.38
Flash Point 311.3±27.8 °C
Exact Mass 480.090393
PSA 212.67000
LogP 1.81
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.705
InChIKey CDRRULDABVKKHU-UHFFFAOYSA-N
SMILES COc1c(O)cc2c(c1O)C1OC(COC(=O)c3cc(O)c(O)c(O)c3)C(O)C(O)C1OC2=O

 Safety Information

Hazard Codes Xi

 11-O-GalloylbergeninBioassay

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Name: Antiglycation activity assessed as inhibition of advanced glycation end product forma...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1809873
Name: Inhibition of NFkappaB signaling pathway in LPS-stimulated mouse RAW264.7 cells by EL...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3825116
Name: Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as dow...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3825117
Name: Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as dow...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3825112
Name: Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at ...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3824927
Name: Antiglycation activity assessed as inhibition of Schiff-base formation at 200 uM
Source: ChEMBL
Target: N/A
External Id: CHEMBL1809867
Name: Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in cel...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3824928
Name: Antioxidant activity assessed as ABTS free radical scavenging activity at 200 uM
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1809866
Name: Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as dow...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3825118
Name: Antiglycation activity in bovine serum albumin assessed as inhibition of fructosamine...
Source: ChEMBL
Target: Albumin
External Id: CHEMBL1809869
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 Synonyms

[(2R,3S,4S,4aR,10bS)-3,4,8,10-Tetrahydroxy-9-methoxy-6-oxo-2,3,4,4a,6,10b-hexahydropyrano[3,2-c]isochromen-2-yl]methyl 3,4,5-trihydroxybenzoate
Benzoic acid, 3,4,5-trihydroxy-, [(2R,3S,4S,4aR,10bS)-2,3,4,4a,6,10b-hexahydro-3,4,8,10-tetrahydroxy-9-methoxy-6-oxopyrano[3,2-c][2]benzopyran-2-yl]methyl ester
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