的K-ras-IN-1

• 常用名: 的K-ras-IN-1
• 英文名: K-Ras-IN-1
• CAS号: 84783-01-7
• 分子量: 207.292
• 密度: 1.3±0.1 g/cm3
• 沸点: 332.1±44.0 °C at 760 mmHg
• 分子式: C₁₁H₁₃NOS
• 熔点: N/A
• 闪点: 154.7±28.4 °C

的K-ras-IN-1用途

K-Ras-IN-1是一种K-ras抑制剂。

的K-ras-IN-1名称

• 中文名: 的K-ras-IN-1
• 英文名: 1-[(2-Hydroxyphenyl)thioxomethyl]pyrrolidine

的K-ras-IN-1生物活性

• 描述: K-Ras-IN-1是一种K-ras抑制剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 拉斯
  研究领域 >> 癌症
• 参考文献:

  [1]. Hocker HJ, et al. LIBSA--a method for the determination of ligand-binding preference to allosteric sites on receptor ensembles. J Chem Inf Model. 2014 Feb 24;54(2):530-538.

  [2]. Sun Q, et al. Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation. Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6140-6143

的K-ras-IN-1物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 332.1±44.0 °C at 760 mmHg
• 分子式: C₁₁H₁₃NOS
• 分子量: 207.292
• 闪点: 154.7±28.4 °C
• 精确质量: 207.071777
• LogP: 2.06
• InChIKey: QIKLOVZAPGSYNO-UHFFFAOYSA-N
• SMILES: Oc1ccccc1C(=S)N1CCCC1
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.668
• 储存条件: 2-8℃

的K-ras-IN-1靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti... 来源：The Scripps Research Institute Molecular Screening Center 靶标：caspase-3 preproprotein [Homo sapiens] External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

共114条，当前第1页，共12页

1

2

3

4

5

的K-ras-IN-1英文别名

• (2-Hydroxyphenyl)(1-pyrrolidinyl)methanethione
• 1-[(2-Hydroxyphenyl)thioxomethyl]pyrrolidine
• (2-Hydroxyphenyl)(1-pyrrolidinyl)methanthion
• (2-Hydroxyphényl)(1-pyrrolidinyl)méthanethione
• K-Ras-IN-1