(R)-Preclamol

• 常用名: (R)-Preclamol
• 英文名: (R)-Preclamol
• CAS号: 85976-54-1
• 分子量: 219.32300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₂₁NO
• 熔点: N/A
• 闪点: N/A

(R)-Preclamol用途

(R) -丙胺前体是一种多巴胺(DA)激动剂,具有自身受体和突触后受体刺激特性。(R) -低剂量的丙泊酚抑制小鼠和大鼠的运动活动[1]。

(R)-Preclamol名称

• 英文名: (+)-preclamol

(R)-Preclamol生物活性

• 描述: (R) -丙胺前体是一种多巴胺(DA)激动剂,具有自身受体和突触后受体刺激特性。(R) -低剂量的丙泊酚抑制小鼠和大鼠的运动活动[1]。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 多巴胺受体
  信号通路 >> 神经信号通路 >> 多巴胺受体
  研究领域 >> 神经疾病
• 靶点实验:

  dopamine[1]

• 参考文献:

  [1]. Hjorth S, et al. Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP.

  [2]. Arnt J, et al. Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers. Psychopharmacology (Berl). 1983;81(3):199-207.

(R)-Preclamol物理化学性质

• 分子式: C₁₄H₂₁NO
• 分子量: 219.32300
• 精确质量: 219.16200
• PSA: 23.47000
• LogP: 2.91950
• InChIKey: HTSNFXAICLXZMA-ZDUSSCGKSA-N
• SMILES: CCCN1CCCC(c2cccc(O)c2)C1

(R)-Preclamol靶点实验

查看更多实验

实验名称：Dose required for postsynaptic agonism using motor activity test in reserpinized rats 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL778421

实验名称：qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay vali... 来源：NCGC External Id：adst_MBL_Abs_LOPAC_o1

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2... 来源：NCGC 靶标：ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] External Id：UBCH001

实验名称：DOPA accumulation in normal rat cortex at 0.8 umol/kg expressed as percent of control... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL781037

实验名称：Late stage Counterscreen for the probe development effort to identify agonists of the... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1_ACT_LUMI_1536_3XEC50_MDCSRUN (HTR2A)

实验名称：Late stage for the probe development effort to identify agonists of the mouse 5-hydro... 来源：The Scripps Research Institute Molecular Screening Center 靶标：5-hydroxytryptamine receptor 2A [Mus musculus] External Id：HTR2A_ACT_LUMI_1536_3XEC50_MDRUN

实验名称：Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand 来源：ChEMBL 靶标：D(2) dopamine receptor External Id：CHEMBL673353

实验名称：DOPA accumulation in normal rat cortex at 27 umol/kg expressed as percent of control;... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL781041

共133条，当前第1页，共14页

1

2

3

4

5

(R)-Preclamol英文别名

• R(+)-3-(3-hydroxyphenyl)-N-propylpiperidine
• (R)-(+)-3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine
• R-(-)-3-(3-hydroxyphenyl)-N-(n-propyl)piperidine
• (R)-(+)-3-[3-hydroxyphenyl]-N-(1-propyl)-piperidine
• 3-(1-Propyl-piperidin-3-yl)-phenol
• R-(+)-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine
• (+)-3-PPP