RSV-IN-3

• 常用名: RSV-IN-3
• 英文名: RSV-IN-3
• CAS号: 862825-90-9
• 分子量: 351.25
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₂Cl₂N₂OS
• 熔点: N/A
• 闪点: N/A

RSV-IN-3用途

RSV-IN-3(化合物1)是呼吸道合胞病毒(RSV)和甲型流感病毒(IAV)的双重抑制剂。RSV-IN-3显示抗RSV活性(EC50 = 32.70 μM[1]。

RSV-IN-3名称

• 英文名: RSV-IN-3

RSV-IN-3生物活性

• 描述: RSV-IN-3(化合物1)是呼吸道合胞病毒(RSV)和甲型流感病毒(IAV)的双重抑制剂。RSV-IN-3显示抗RSV活性(EC50 = 32.70 μM[1]。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
  信号通路 >> 抗感染 >> RSV
• 参考文献:

  [1]. Guo-Ning Zhang, et al. Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A. Eur J Med Chem. 2020 Jan 15;186:111861.

RSV-IN-3物理化学性质

• 分子式: C₁₆H₁₂Cl₂N₂OS
• 分子量: 351.25
• InChIKey: OUNROJVGCGSCFI-UHFFFAOYSA-N
• SMILES: O=C(CSc1c[nH]c2ccccc12)Nc1ccc(Cl)c(Cl)c1

RSV-IN-3靶点实验

查看更多实验

实验名称：Antiviral activity against GFP-fused wild-type RSV subgroup A Long infected in human ... 来源：ChEMBL 靶标：Respiratory syncytial virus External Id：CHEMBL4722359

实验名称：Screen for inhibitors of RMI FANCM (MM2) intereaction 来源：11908 靶标：N/A External Id：RMI-FANCM-MM2

实验名称：Cytotoxicity against human HEp-2 cells assessed as cell viability at 50 uM measured a... 来源：ChEMBL 靶标：HEp-2 External Id：CHEMBL4722378

实验名称：Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability measur... 来源：ChEMBL 靶标：HEp-2 External Id：CHEMBL4722360

实验名称：Safety index, ratio of CC50 for human HEp-2 cells to EC50 for GFP-fused wild-type RSV... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4722361

实验名称：Antiviral activity against GFP-fused wild-type RSV subgroup A Long infected in human ... 来源：ChEMBL 靶标：Respiratory syncytial virus External Id：CHEMBL4722377

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