(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐

• 常用名: (S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐
• 英文名: PRECLAMOL HYDROCHLORIDE
• CAS号: 88768-67-6
• 分子量: 255.78
• 密度: N/A
• 沸点: 342.2ºC at 760 mmHg
• 分子式: C₁₄H₂₂ClNO
• 熔点: N/A
• 闪点: 158ºC

用途

盐酸普瑞拉莫尔((-)-3-聚丙烯盐酸盐)是一种选择性多巴胺自身受体激动剂。盐酸普瑞拉莫尔具有研究精神分裂症的潜力[1][2]。

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐名称

• 中文名: (S)-(-)-3-(3-羟基苯基)-N-丙基哌啶 盐酸盐
• 英文名: 3-[(3S)-1-Propyl-3-piperidinyl]phenol hydrochloride (1:1)

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐生物活性

• 描述: 盐酸普瑞拉莫尔((-)-3-聚丙烯盐酸盐)是一种选择性多巴胺自身受体激动剂。盐酸普瑞拉莫尔具有研究精神分裂症的潜力[1][2]。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 多巴胺受体
  信号通路 >> 神经信号通路 >> 多巴胺受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Seth-Olov Thorberg, et al. Large scale synthesis and absolute configuration of (-)-3-ppp, a selective dopamine autoreceptor agonist. Tetrahedron. 1985, 41(1): 129-139.

  [2]. Tamminga CA, et al. Pharmacologic properties of (-)-3PPP (preclamol) in man. J Neural Transm Gen Sect. 1992;88(3):165-75.

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐物理化学性质

• 沸点: 342.2ºC at 760 mmHg
• 分子式: C₁₄H₂₂ClNO
• 分子量: 255.78
• 闪点: 158ºC
• 精确质量: 255.13900
• PSA: 23.47000
• LogP: 3.72150
• InChIKey: NRHUDETYKUBQJT-BTQNPOSSSA-N
• SMILES: CCCN1CCCC(c2cccc(O)c2)C1.Cl

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐MSDS

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐MSDS英文版

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3
• 海关编码: 2933399090

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐海关

• 海关编码: 2933399090
• 中文概述: 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐靶点实验

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实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Evaluated for dopa accumulation (biochemical activity) in rat striatum 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL778857

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