4-(N-(1,8-萘酰亚胺))-N-丁酸

• 常用名: 4-(N-(1,8-萘酰亚胺))-N-丁酸
• 英文名: Virstatin
• CAS号: 88909-96-0
• 分子量: 283.28
• 密度: 1.403g/cm3
• 沸点: 536.5ºC at 760 mmHg
• 分子式: C₁₆H₁₃NO₄
• 熔点: N/A
• 闪点: 278.3ºC

4-(N-(1,8-萘酰亚胺))-N-丁酸用途

Virstatin 抑制菌毛系统合成并阻止 A. baumannii 生物膜的形成。Virstatin 还抑制转录激活剂 ToxT 的二聚化。

4-(N-(1,8-萘酰亚胺))-N-丁酸名称

• 中文名: 4-(N-(1,8-萘酰亚胺))-N-丁酸
• 英文名: 4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanoic acid

4-(N-(1,8-萘酰亚胺))-N-丁酸生物活性

• 描述: Virstatin 抑制菌毛系统合成并阻止 A. baumannii 生物膜的形成。Virstatin 还抑制转录激活剂 ToxT 的二聚化。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 靶点实验:

  ToxT[1]

• 参考文献:

  [1]. Nait Chabane Y, et al. Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii. BMC Microbiol. 2014 Mar 12;14:62.

  [2]. Shakhnovich EA, et al. Virstatin inhibits dimerization of the transcriptional activator ToxT. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2372-7.

4-(N-(1,8-萘酰亚胺))-N-丁酸物理化学性质

• 密度: 1.403g/cm3
• 沸点: 536.5ºC at 760 mmHg
• 分子式: C₁₆H₁₃NO₄
• 分子量: 283.28
• 闪点: 278.3ºC
• 精确质量: 283.08400
• PSA: 76.37000
• LogP: 1.81750
• InChIKey: ZHXRDXTYPCPBTI-UHFFFAOYSA-N
• SMILES: O=C(O)CCCN1C(=O)c2cccc3cccc(c23)C1=O
• 折射率: 1.672
• 储存条件: -20°C，密闭，干燥

4-(N-(1,8-萘酰亚胺))-N-丁酸MSDS

4-(N-(1,8-萘酰亚胺))-N-丁酸MSDS英文版

4-(N-(1,8-萘酰亚胺))-N-丁酸毒性和生态

4-(N-(1,8-萘酰亚胺))-N-丁酸安全信息

• 海关编码: 2933990090

4-(N-(1,8-萘酰亚胺))-N-丁酸海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-(N-(1,8-萘酰亚胺))-N-丁酸靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：ERK5 transcriptional activity HTS 来源：24565 靶标：N/A External Id：ERK5 transcriptional activity-HTS

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

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4-(N-(1,8-萘酰亚胺))-N-丁酸英文别名

• Isodibut
• 1,8-naphthalimide-N-butyric acid
• 1H-Benz(de)isoquinoline-2(3H)-butanoic acid,1,3-dioxo
• Virstatin
• 4-(N-(1,8-naphthalimide))-n-butyric acid
• 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butanoic acid
• 4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid
• 4-(1,3-dioxo-2,3-dihydro-1H-benzo[d,e]isoquinolin-2-yl)butanoic acid
• 4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyric acid
• 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butyric acid
• (1,8-naphthalimido)butanoic acid
• N-(4-butanoic acid)-1,8-naphthalimide