Anti-inflammatory agent 14

• 常用名: Anti-inflammatory agent 14
• 英文名: Anti-inflammatory agent 14
• CAS号: 894496-27-6
• 分子量: 300.38
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₆N₂O₂S
• 熔点: N/A
• 闪点: N/A

Anti-inflammatory agent 14用途

抗炎剂14(化合物28)是一种抗炎剂,Mtb H37Rv的MIC50为2μM【1】。

Anti-inflammatory agent 14名称

• 英文名: Anti-inflammatory agent 14

Anti-inflammatory agent 14生物活性

• 描述: 抗炎剂14(化合物28)是一种抗炎剂,Mtb H37Rv的MIC50为2μM【1】。
• 相关类别:
  研究领域 >> 感染
  研究领域 >> 炎症/免疫
  信号通路 >> 抗感染 >> 细菌
• 体外研究: 抗炎剂14(化合物28)剂量依赖性地抑制IL-1β[1]。
• 参考文献:

  [1]. Sanderson Dias Calixto, et al. Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis. Bioorg Med Chem. 2022 Jan 1;53:116506.

Anti-inflammatory agent 14物理化学性质

• 分子式: C₁₆H₁₆N₂O₂S
• 分子量: 300.38
• InChIKey: NILPSABXLUXHCD-UHFFFAOYSA-N
• SMILES: S=C(NCc1ccccc1)Nc1ccc2c(c1)OCCO2

Anti-inflammatory agent 14靶点实验

查看更多实验

实验名称：Selectivity index, ratio of CC50 for cytotoxicity against LPS-stimulated mouse RAW264... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5144866

实验名称：Antitubercular activity against Mycobacterium tuberculosis H37Rv infected in mouse RA... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL5144869

实验名称：Anti-inflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as re... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5144862

实验名称：Selectivity index, ratio of CC50 for cytotoxicity against LPS-stimulated mouse RAW264... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5144858

实验名称：Inhibition of NO production in mouse RAW264.7 cells incubated for 24 hrs by Griess re... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5144859

实验名称：Anti-inflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as re... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5144860

实验名称：Antitubercular activity against Mycobacterium tuberculosis H37Rv assessed as reductio... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL5144856

实验名称：Cytotoxicity against LPS-stimulated mouse RAW264.7 cells after 24 hrs by MTT assay 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5144857

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