阿贝卡尔杂质4

• 常用名: 阿贝卡尔杂质4
• 英文名: AZD5099
• CAS号: 907543-25-3
• 分子量: 548.44
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₇Cl₂N₅O₆S
• 熔点: N/A
• 闪点: N/A

阿贝卡尔杂质4用途

AZD5099是一种抗菌剂,是一种高效、选择性的细菌拓扑异构酶II抑制剂。AZD5099能有效抑制革兰氏阳性和挑剔的革兰氏阴性细菌引起的感染[1]。

阿贝卡尔杂质4名称

• 中文名: 阿贝卡尔杂质4
• 英文名: kgzhravdxgquqm-wcqgtbresa-n

阿贝卡尔杂质4生物活性

• 描述: AZD5099是一种抗菌剂,是一种高效、选择性的细菌拓扑异构酶II抑制剂。AZD5099能有效抑制革兰氏阳性和挑剔的革兰氏阴性细菌引起的感染[1]。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 拓扑异构酶
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  Topoisomerase II

• 参考文献:

  [1]. Gregory S Basarab, et al. Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099). J Med Chem. 2014 Jul 24;57(14):6060-82.

阿贝卡尔杂质4物理化学性质

• 分子式: C₂₁H₂₇Cl₂N₅O₆S
• 分子量: 548.44
• InChIKey: KGZHRAVDXGQUQM-WCQGTBRESA-N
• SMILES: COCC(C)NC(=O)c1nc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)C(OC)C2)sc1C(=O)O

阿贝卡尔杂质4靶点实验

查看更多实验

实验名称：Antimicrobial activity against Staphylococcus aureus by broth microdilution/CLSI meth... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3363592

实验名称：Antimicrobial activity against methicillin-resistant Staphylococcus aureus by broth m... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3363593

实验名称：Antibacterial activity against methicillin-sensitive Staphylococcus aureus assessed a... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3363590

实验名称：Antibacterial activity against methicillin-sensitive Staphylococcus aureus assessed a... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3363591

实验名称：Antimicrobial activity against Enterococcus faecium by broth microdilution/CLSI metho... 来源：ChEMBL 靶标：Enterococcus faecium External Id：CHEMBL3363596

实验名称：Antimicrobial activity against vancomycin-resistant Enterococcus faecium by broth mic... 来源：ChEMBL 靶标：Enterococcus faecium External Id：CHEMBL3363597

实验名称：Antimicrobial activity against Enterococcus faecalis by broth microdilution/CLSI meth... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL3363594

实验名称：Antimicrobial activity against vancomycin-resistant Enterococcus faecalis by broth mi... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL3363595

实验名称：Antimicrobial activity against 2 times drug resistance selected Staphylococcus aureus... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3363600

实验名称：Antimicrobial activity against 2 times drug resistance selected Staphylococcus aureus... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3363601

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