![]() ConantokinG结构式
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常用名 | ConantokinG | 英文名 | Conantokin G |
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CAS号 | 93438-65-4 | 分子量 | 2264.19000 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C88H138N26O44 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | N/A |
ConantokinG用途本网站展示的所有产品仅用作科学研究,不可食用,不可用于人体或动物的临床诊断和治疗。
Conantokin G 是一种 17 个氨基酸的肽,是一种有效,选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G 抑制鼠皮质神经元中 NMDA 诱发的电流,IC50 为 480 nM,具有神经保护作用。 |
中文名 | GLY-GLU-GLA-GLA-LEU-GLN-GLA-ASN-GLN-GLA-LEU-ILE-ARG-GLA-LYS-SER-ASN-NH2 |
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英文名 | conantokin g |
英文别名 | 更多 |
描述 | Conantokin G 是一种 17 个氨基酸的肽,是一种有效,选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G 抑制鼠皮质神经元中 NMDA 诱发的电流,IC50 为 480 nM,具有神经保护作用。 |
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相关类别 | |
参考文献 |
分子式 | C88H138N26O44 |
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分子量 | 2264.19000 |
精确质量 | 2262.94000 |
PSA | 1225.52000 |
外观性状 | 白色冻干的固体 |
储存条件 | -20°C |
个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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危害码 (欧洲) | Xi |
危险品运输编码 | NONH for all modes of transport |
NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.
Curr. Drug Targets. CNS Neurol. Disord. 4(2) , 143-51, (2005) Glutamate is the main excitatory neurotransmitter in the central nervous system and it plays a significant role not only in synaptic transmission but also in acute and chronic neuropathologies includi... |
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The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs.
Epilepsy Res. 59(1) , 13-24, (2004) The N-methyl-D-aspartate (NMDA) receptor-gated ion channel is comprised of at least one NR1 subunit and any of four NR2 subunits (NR2A-D). The NR2 subunit confers different pharmacological and kinetic... |
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The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B.
Neuropharmacology 57(2) , 127-36, (2009) The conantokins are short, naturally occurring peptides that inhibit ion flow through N-methyl-d-aspartate receptor (NMDAR) channels. One member of this peptide family, conantokin-G (con-G), shows hig... |
'SLEEPER PEPTIDE' |
H-GLY-GLU-GLA-GLA-LEU-GLN-GLA-ASN-GLN-GLA-LEU-ILE-ARG-GLA-LYS-SER-ASN-NH2 |
conotoxin GV |
M.W. 2264.1 C88H138N26O44 |
GLY-GLU-GLA-GLA-LEU-GLN-GLA-ASN-GLN-GLA-LEU-ILE-ARG-GLA-LYS-SER-ASN-NH2 |
Conotoxin GV,Sleeper Peptide |