HDAC1,2-IN-2

• 常用名: HDAC1,2-IN-2
• 英文名: HDAC1,2-IN-2
• CAS号: 937727-03-2
• 分子量: 449.529
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₃N₅O₃S
• 熔点: N/A
• 闪点: N/A

HDAC1,2-IN-2用途

A potent, selective HDAC1 and HDAC2 inhibitor with IC50 of 6 nM and 45 nM, respectively; displays highly selectivity over HDAC3 (IC50=7.0 μM), HDAC8 and 11 (IC50=20-25 uM) and no activity on HDACs 4-7; increases lysine 5 of histone H2B (H2BK5) in HCT116 colon carcinoma cells with IC50 of 400 nM, inhibited the cell growth with GI50 of 97 nM; exhibits tumor growth inhibition in HCT116 xenograft mice.

HDAC1,2-IN-2名称

• 英文名: HDAC1,2-IN-2

HDAC1,2-IN-2物理化学性质

• 分子式: C₂₃H₂₃N₅O₃S
• 分子量: 449.529