5-羟基噻苯咪唑

更新时间：2025-08-22 12:50:13

5-羟基噻苯咪唑结构式	常用名	5-羟基噻苯咪唑	英文名	5-hydroxy Thiabendazole
	CAS号	948-71-0	分子量	217.25
	密度	1.535g/cm3	沸点	525.6ºC at 760mmHg
	分子式	C₁₀H₇N₃OS	熔点	N/A
	MSDS	中文版美版	闪点	271.7ºC
	符号	GHS07, GHS09	信号词	Warning

5-羟基噻苯咪唑用途

5-Hydroxythiabendazole(5-OHTBZ)是 Thiabendazole(HY-B0263)暴露的生物标志物。

中文名	噻苯咪唑-5-羟基
英文名	5-Hydroxy Thiabendazole
中文别名	5-羟基噻苯咪唑
英文别名	更多

描述	5-Hydroxythiabendazole(5-OHTBZ)是 Thiabendazole(HY-B0263)暴露的生物标志物。
相关类别	研究领域 >> 其他
参考文献	[1]. STONE OJ, et al. COMPARISON OF THIABENDAZOLE AND 5-HYDROXY-THIABENDAZOLE (FOR ANTHELMINTIC EFFECT). J Invest Dermatol. 1965 Aug;45:132-3.

密度	1.535g/cm3
沸点	525.6ºC at 760mmHg
分子式	C₁₀H₇N₃OS
分子量	217.25
闪点	271.7ºC
精确质量	217.03100
PSA	90.04000
LogP	2.39200
InChIKey	VNENJHUOPQAPAT-UHFFFAOYSA-N
SMILES	Oc1ccc2nc(-c3cscn3)[nH]c2c1
折射率	1.783
储存条件	0-6°C

符号	GHS07, GHS09
信号词	Warning
危害声明	H302-H400
警示性声明	P273
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xn,N
风险声明 (欧洲)	22-50/53
安全声明 (欧洲)	60-61
危险品运输编码	UN 3077
包装等级	III
危险类别	9
海关编码	2934999090

噻菌灵

148-79-8

5-羟基噻苯咪唑

948-71-0

文献：Xenobiotica, , vol. 26, # 7 p. 765 - 778

5-羟基噻苯咪唑上游产品 1
CAS号148-79-8 噻菌灵
5-羟基噻苯咪唑下游产品 1
CAS号962-28-7 5-羟基噻菌灵硫酸盐

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.

J. AOAC Int. 98(1) , 230-47, (2015)

Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using ...

Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells.

Chem. Biol. Interact. 127(2) , 109-24, (2000)

Thiabendazole (TBZ), an anthelmintic and fungicide benzimidazole, was recently demonstrated to be extensively metabolized by cytochrome P450 (CYP) 1A2 in man and rabbit, yielding 5-hydroxythiabendazol...

In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions.

Drug Metab. Dispos. 37 , 1286-1294, (2009)

Thiabendazole (TBZ) and its major metabolite 5-hydroxythiabendazole (5OH-TBZ) were screened for potential time-dependent inhibition (TDI) against CYP1A2. Screen assays were carried out in the absence ...

2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-ol