龙血素C

• 常用名: 龙血素C
• 英文名: Cochinchinenin C
• CAS号: 956103-79-0
• 分子量: 542.619
• 密度: 1.2±0.1 g/cm3
• 沸点: 767.2±60.0 °C at 760 mmHg
• 分子式: C₃₃H₃₄O₇
• 熔点: N/A
• 闪点: 247.5±26.4 °C

龙血素C用途

可可碱C是胰高血糖素样肽-1(GLP-1)受体的非多肽激动剂。可可碱C可用于糖尿病的研究[1][2]。

龙血素C名称

• 中文名: 剑叶龙血素 C
• 英文名: Cochinchinenin C
• 中文别名: 龙血素C

龙血素C生物活性

• 描述: 可可碱C是胰高血糖素样肽-1(GLP-1)受体的非多肽激动剂。可可碱C可用于糖尿病的研究[1][2]。
• 相关类别:
  研究领域 >> 代谢疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 胰高血糖素受体
• 靶点实验:

  glucagon-like peptide-1 receptor[1][2]

• 参考文献:

  [1]. Sha Y et, al. Cochinchinenin C, a potential nonpolypeptide anti-diabetic drug, targets a glucagon-like peptide-1 receptor. RSC Adv., 2017, 7, 49015-49023.

  [2]. Chen X, et, al. Comparison between loureirin A and cochinchinenin C on the interaction with human serum albumin. Eur J Med Chem. 2015 Mar 26;93:492-500.

龙血素C物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 767.2±60.0 °C at 760 mmHg
• 分子式: C₃₃H₃₄O₇
• 分子量: 542.619
• 闪点: 247.5±26.4 °C
• 精确质量: 542.230469
• PSA: 105.45000
• LogP: 6.26
• InChIKey: SLJWKFROLINAGW-UHFFFAOYSA-N
• SMILES: COc1ccc(C(CCc2ccc(O)cc2OC)c2cc(CCC(=O)c3ccc(O)cc3)c(OC)cc2O)cc1
• 外观性状: 粉末
• 蒸汽压: 0.0±2.7 mmHg at 25°C
• 折射率: 1.619
• 储存条件: 2-8°C，密封，干燥

龙血素C靶点实验

查看更多实验

实验名称：Binding affinity to human serum albumin assessed as Stem-Volmer quenching constant at... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411727

实验名称：Binding affinity to human serum albumin assessed as Stem-Volmer quenching constant at... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411728

实验名称：Binding affinity to human serum albumin assessed as quenching constant at 305K by flu... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411731

实验名称：Binding affinity to human serum albumin assessed as quenching constant at 310K by flu... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411732

实验名称：Binding affinity to human serum albumin assessed as Stem-Volmer quenching constant at... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411729

实验名称：Binding affinity to human serum albumin assessed as quenching constant at 300K by flu... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411730

实验名称：Binding affinity to human serum albumin assessed as binding constant at 305K by Stem-... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411735

实验名称：Binding affinity to human serum albumin assessed as binding constant at 310K by Stem-... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411736

实验名称：Binding affinity to human serum albumin by UV-vis spectrophotometry 来源：ChEMBL 靶标：Albumin External Id：CHEMBL3411733

实验名称：Antibacterial activity against Helicobacter pylori ATCC 43504 by agar dilution method 来源：ChEMBL 靶标：Helicobacter pylori External Id：CHEMBL925660

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龙血素C英文别名

• 3-{4-Hydroxy-5-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-methoxyphenyl)propyl]-2-methoxyphenyl}-1-(4-hydroxyphenyl)propan-1-one
• Loureirin C
• 3-{4-Hydroxy-5-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-methoxyphenyl)propyl]-2-methoxyphenyl}-1-(4-hydroxyphenyl)-1-propanone