美曲勃龙结构式
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常用名 | 美曲勃龙 | 英文名 | Methyltrienolone |
|---|---|---|---|---|
| CAS号 | 965-93-5 | 分子量 | 284.393 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 485.9±45.0 °C at 760 mmHg | |
| 分子式 | C19H24O2 | 熔点 | 206-209 °C | |
| MSDS | 中文版 美版 | 闪点 | 206.3±21.3 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
美曲勃龙用途An orally active anabolic-androgenic steroid and a 19-nortestosterone derivative that has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.. |
| 中文名 | 美曲勃龙 |
|---|---|
| 英文名 | 17β-hydroxy-17-methylestra-4,9,11-trien-3-one |
| 中文别名 | 17Α-甲基-17Β-羟基雌-4,9,11-三烯-3-酮 |
| 英文别名 | 更多 |
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 485.9±45.0 °C at 760 mmHg |
| 熔点 | 206-209 °C |
| 分子式 | C19H24O2 |
| 分子量 | 284.393 |
| 闪点 | 206.3±21.3 °C |
| 精确质量 | 284.177643 |
| PSA | 37.30000 |
| LogP | 2.81 |
| 蒸汽密度 | 5.31 (vs air) |
| 蒸汽压 | 0.0±2.8 mmHg at 25°C |
| 折射率 | 1.597 |
| 储存条件 | 2-8°C |
| 水溶解性 | INSOLUBLE |
| 分子结构 | 1、 摩尔折射率：82.52 2、 摩尔体积（cm3/mol）：242.0 3、 等张比容(90.2K)：635.4 4、 表面张力(dyne/cm)：47.4 5、 极化率(10-24cm3)：32.71 |
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H319 |
| 警示性声明 | P305 + P351 + P338 |
| 危害码 (欧洲) | F,Xi |
| 风险声明 (欧洲) | R11:Highly Flammable. R43:May cause sensitization by skin contact. |
| 安全声明 (欧洲) | S16-S36/37 |
| 危险品运输编码 | UN 1312 4.1/PG 3 |
| WGK德国 | 2 |
| RTECS号 | DT5095000 |
| 包装等级 | III |
| 危险类别 | 4.1 |
| 海关编码 | 29061900 |
| 海关编码 | 29061900 |
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Bisphenol A affects androgen receptor function via multiple mechanisms
Chem. Biol. Interact. 203(3) , 556-64, (2013) • BPA antagonizes AR function by competitive inhibition of androgen binding. • Prevents functional foci formation in the nucleus. • Reduce the AR presence in the nucleus. • BPAF have similar activatio... |
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Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice.
Oncotarget 6(8) , 6136-50, (2015) There is a critical need for therapeutic agents that can target the amino-terminal domain (NTD) of androgen receptor (AR) for the treatment of castration-resistant prostate cancer (CRPC). Calmodulin (... |
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The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.
Oncotarget 5(6) , 1666-82, (2014) Prostate cancer (PCa) is among the leading causes of cancer-related death in men. Androgen receptor (AR) signaling plays a seminal role in prostate development and homeostasis, and dysregulation of th... |
| 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one |
| 17a-Methyl-3-oxo-4,9,11-estratrien-17b-ol |
| 17α-Methyl-17β-hydroxyestra-4,9(10),11-trien-3-one |
| Methyltrienolone |
| (17β)-17-hydroxy-17-methyl-estra-4,9,11-triene-3-one |
| (17b)-17-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| 17-β-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| 17α-Methyltrienolone |
| 17α-Methyl-17β-hydroxyestra-4,9,11-trien-3-one |
| 17-β-hydroxy-17-methylestra-4,9,11-trien-3-one (9CI) |
| 3-Oxo-17β-hydroxy-17α-methylestra-4,9,11-triene |
| 17A-METHYL-TRENBOLONE |
| (17b)-17-Hydroxy-17-methyl-estra-4,9,11-trien-3-one |
| 17a-Methyl-4,9,11-estratrien-17b-ol-3-one |
| 3-Oxo-17b-hydroxy-17-methylestra-4,9,11-triene |
| 17α-Methyl-3-oxo-4,9,11-estratrien-17β-ol |
| Estra-4,9,11-trien-3-one, 17-hydroxy-17-methyl-, (17β)- |
| 17a-Methyl-17b-hydroxyestra-4,9(10),11-trien-3-one |
| 17b-Hydroxy-17-methyl-19-norandrosta-4,9,11-trien-3-one |
| Estra-4,9,11-trien-3-one, 17β-hydroxy-17-methyl- |
| 17-β-hydroxy-17-methyl-19-norandrosta-4,9,11-triene-3-one |
| 17β-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| Methyl trenbolone(Metribolone) |
| MFCD00199021 |
| R1881 |
| 3-Oxo-17b-hydroxy-17a-methylestra-4,9,11-triene |
| 17a-Methyltrienolone |
| 17a-Methyl-17b-hydroxyestra-4,9,11-trien-3-one |
| 17b-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| 3-Oxo-17β-hydroxy-17-methylestra-4,9,11-triene |
| RU-1881 |
| Metribolone |
| (17β)-17-Hydroxy-17-methylestra-4,9,11-trien-3-one |
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